Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CCL2 | P13500 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27457482 | 0.89 | — | — | |
| SCHEMBL7611904 | 0.88 | CYP2D6 (0.33) | CYP2D6 | |
| SCHEMBL6555624 | 0.83 | HTR6 (0.33) | HTR6HTR2ACYP2D6SIGMAR1KDM4E | |
| SCHEMBL6446741 | 0.81 | HTR6 (0.31) | HTR6HTR2A | |
| SCHEMBL6445322 | 0.81 | — | — | |
| SCHEMBL6449636 | 0.80 | — | — | |
| SCHEMBL3380394 | 0.79 | HTR2A (0.35) | HTR6HTR2ACYP2D6SIGMAR1BRD4 | |
| SCHEMBL436484 | 0.79 | ATM (0.33) | HTR6HTR2A | |
| SCHEMBL6476669 | 0.79 | — | — | |
| SCHEMBL6448204 | 0.79 | KDM4E (0.31) | HTR6HTR2ACYP2D6KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 320 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6641925-B1 | Metallocene system catalyzed cycloolefin copolymer laminated to polyvinyl chloride; extrusion coated film as packaging | TICONA GMBH (DE) | 2003-11-04 | — | — | US | claimed |
| US-6063880-A | VIA SOLUTION, SUSPENSION, OR GAS PHASE HOMO- OR CO-POLYMERIZATION OF OLEFINS OF GIVEN FORMULA IN THE PRESENCE OF A CATALYST CONSISTING OF A METALLOCENE AND ALUMOXANE OF GIVEN FORMULAS; SIMPLIFICATION: NO HYDROGEN GAS NEEDED | TARGOR GMBH (DE) | 2000-05-16 | — | — | US | claimed |
| US-5962719-A | Process for the preparation of a polyolefin wax | TARGOR GMBH (DE) | 1999-10-05 | — | — | US | claimed |
| EP-0416566-B1 | Process for preparing a polyolefine wax | TARGOR GMBH (DE) | 1999-07-14 | — | — | EP | claimed |
| US-5698645-A | POLYMERIZING AT LEAST ONE CYCLOOLEFIN AND ONE ACYCLIC OLEFIN IN THE PRESENCE OF A METALLOCENE CATALYST AND A COCATALYST | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-16 | — | — | US | claimed |
| JP-10158287-A | — | — | None | — | — | JP | disclosed |
| US-12398167-B2 | Process for producing metallocenes | LANXESS ORGANOMETALLICS GMBH (DE) | 2025-08-26 | — | — | US | disclosed |
| WO-2024185503-A1 | RESIN MODIFIER AND RESIN COMPOSITION COMPRISING SAME | 東ソー株式会社 | 2024-09-12 | — | — | WO | disclosed |
| US-11643485-B2 | Ethylene-based polymer, polyethylene-based resin composition and use thereof, catalyst component for olefin polymerization, olefin polymerization catalyst containing the component, and method for producing ethylene-based polymer by using the catalyst | JAPAN POLYETHYLENE CORPORATION (JP) | 2023-05-09 | — | — | US | disclosed |
| EP-3917938-A1 | PROCESS FOR PRODUCING METALLOCENES | LANXESS Organometallics GmbH (DE) | 2021-12-08 | — | — | EP | disclosed |
| US-11192976-B2 | Copolymer, polymer, molding material and resin molded body | ZEON CORPORATION (JP) | 2021-12-07 | — | — | US | disclosed |
| WO-2020156998-A1 | PROCESS FOR PRODUCING METALLOCENES | LANXESS ORGANOMETALLICS GMBH (DE) | 2020-08-06 | — | — | WO | disclosed |
| EP-0498675-A2 | Production of alpha-olefin polymers | MITSUBISHI CHEMICAL CORPORATION (JP) | 1992-08-12 | — | — | EP | disclosed |
| US-5120696-A | OLEFIN POLYMERIZATION CATALYST AND PROCESS FOR THE POLYMERIZATION OF OLEFINS | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0487278-A2 | Functionalized olefin polymers | MITSUBISHI CHEMICAL CORPORATION (JP) | 1992-05-27 | — | — | EP | disclosed |
| EP-0447035-A2 | Method for the preparation of ethylene polymer compositions | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-09-18 | — | — | EP | disclosed |
| EP-0442725-A2 | Olefin polymerization solid catalysts and process for the polymerization of olefins | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-08-21 | — | — | EP | disclosed |
| EP-0439964-A2 | Olefin polymerization catalyst and process for the polymerization of olefins | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-08-07 | — | — | EP | disclosed |
| EP-0436399-A2 | Olefin polymerization catalyst and process for the polymerization of olefins | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-07-10 | — | — | EP | disclosed |
| EP-0370753-A2 | Modified polyolefin particles and process for preparation thereof | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1990-05-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12398167-B2 | Process for producing metallocenes | CYP4F2, PRDX2, PRXL2A | HTR6 4463/4885HTR2A 3539/4885CYP2D6 859/4885 |
| US-11192976-B2 | Copolymer, polymer, molding material and resin molded body | MALT1, CCT7, ALOX15 | HTR6 4475/4885HTR2A 4458/4885CYP2D6 1708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.