SCHEMBL436484

SCHEMBL436484

Cl[Zr](Cl)(=C(c1ccccc1)c1ccccc1)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
HTR6 P50406 1/20 0.31
HTR2A P28223 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25418756 0.90 ATM (0.30) ATM
SCHEMBL566022 0.88
SCHEMBL2861112 0.81 LMNA (0.31) MEN1KMT2A
SCHEMBL273052 0.79 HTR6 (0.33) HTR6HTR2A
SCHEMBL7635192 0.79 SIGMAR1 (0.34) HTR6
SCHEMBL2857578 0.78
SCHEMBL2866685 0.78 CA12 (0.31)
SCHEMBL8855996 0.76 TDP1 (0.30)
SCHEMBL2862464 0.75 LMNA (0.33) MEN1KMT2A
SCHEMBL2862243 0.75 EDNRB (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8969482-B2 Dynamic modulation of metallocene catalysts EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-03-03 US claimed
EP-2760895-A2 DYNAMIC MODULATION OF METALLOCENE CATALYSTS Exxon-Mobil Chemical Patents Inc. (US) 2014-08-06 EP claimed
US-20130085232-A1 Dynamic Modulation of Metallocene Catalysts EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-04-04 US claimed
WO-2013048848-A2 DYNAMIC MODULATION OF METALLOCENE CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-04-04 WO claimed
US-5698645-A POLYMERIZING AT LEAST ONE CYCLOOLEFIN AND ONE ACYCLIC OLEFIN IN THE PRESENCE OF A METALLOCENE CATALYST AND A COCATALYST HOECHST AKTIENGESELLSCHAFT (DE) 1997-12-16 US claimed
WO-2024185503-A1 RESIN MODIFIER AND RESIN COMPOSITION COMPRISING SAME 東ソー株式会社 2024-09-12 WO disclosed
US-11192976-B2 Copolymer, polymer, molding material and resin molded body ZEON CORPORATION (JP) 2021-12-07 US disclosed
US-20200231745-A1 COPOLYMER, POLYMER, MOLDING MATERIAL AND RESIN MOLDED BODY ZEON CORPORATION (JP) 2020-07-23 US disclosed
US-10647811-B2 Copolymer, polymer, molding material and resin molded body ZEON CORPORATION (JP) 2020-05-12 US disclosed
US-20180086877-A1 COPOLYMER, POLYMER, MOLDING MATERIAL AND RESIN MOLDED BODY ZEON CORPORATION (JP) 2018-03-29 US disclosed
US-9919300-B2 1-hexene production process SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-03-20 US disclosed
EP-2484685-B1 TRANSITION METAL COMPLEX, PREPARATION METHOD FOR SAID TRANSITION METAL COMPLEX, TRIMERIZATION CATALYST, PREPARATION METHOD FOR 1-HEXENE, PREPARATION METHOD FOR ETHYLENE POLYMER, SUBSTITUTED CYCLOPENTADIENE COMPOUND, AND PREPARATION METHOD FOR SAID SUBSTITUTED CYCLOPENTADIENE COMPOUND SUMITOMO CHEMICAL CO (JP) 2017-11-01 EP disclosed
US-5698645-A POLYMERIZING AT LEAST ONE CYCLOOLEFIN AND ONE ACYCLIC OLEFIN IN THE PRESENCE OF A METALLOCENE CATALYST AND A COCATALYST HOECHST AKTIENGESELLSCHAFT (DE) 1997-12-16 US disclosed
EP-0612769-B1 Process for producing ethylene alpha-olefin copolymer TOSOH CORP (JP) 1997-11-12 EP disclosed
US-5670681-A Process for preparing a carbon-bridged biscyclopentadiene compound HOECHST AKTIENGESELLSCHAFT (DE) 1997-09-23 US disclosed
EP-0648786-B1 Process for producing alpha-olefin polymer TOSOH CORP (JP) 1997-07-16 EP disclosed
US-5576259-A POLYMERIZATION CATALYST INCLUDING METALLOCENE COMPOUND, IONIC COMPOUND, ORGANOALUMINUM COMPOUND, AND LEWIS BASE TOSOH CORPORATION (JP) 1996-11-19 US disclosed
EP-0653445-A1 Ethylene/alpha-olefin copolymer Tosoh Corporation (JP) 1995-05-17 EP disclosed
EP-0648786-A1 Process for producing alpha-olefin polymer Tosoh Corporation (JP) 1995-04-19 EP disclosed
EP-0612769-A1 Process for producing ethylene alpha-olefin copolymer TOSOH CORPORATION (JP) 1994-08-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10647811-B2 Copolymer, polymer, molding material and resin molded body MALT1, ALOX15, ALOX5 ATM 3244/4885MEN1 1724/4885KMT2A 4418/4885
US-20180086877-A1 COPOLYMER, POLYMER, MOLDING MATERIAL AND RESIN MOLDED BODY MALT1, ALOX15, ALOX5 ATM 3244/4885MEN1 1724/4885KMT2A 4418/4885
US-11192976-B2 Copolymer, polymer, molding material and resin molded body MALT1, CCT7, ALOX15 ATM 3772/4885MEN1 2084/4885KMT2A 4338/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.