Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 16/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.42 |
| ▸ | AR | P10275 | 3/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8856767 | 0.84 | ALDH1A1 (0.49) | PGRALDH1A1HSD17B10CYP3A4TDP1 | |
| SCHEMBL27306362 | 0.77 | PGR (0.31) | PGR | |
| SCHEMBL27306926 | 0.73 | MGAT2 (0.35) | ALDH1A1CYP3A4TDP1HPGDKDM4E | |
| SCHEMBL30973137 | 0.72 | PGR (0.62) | PGRALDH1A1HSD17B10CYP3A4TDP1 | |
| SCHEMBL8856837 | 0.72 | PGR (0.62) | PGRALDH1A1HSD17B10CYP3A4TDP1 | |
| SCHEMBL31395941 | 0.67 | KDM4E (0.72) | PGRALDH1A1HSD17B10CYP3A4TDP1 | |
| SCHEMBL11653695 | 0.66 | ALDH1A1 (0.56) | PGRALDH1A1HSD17B10CYP3A4TDP1 | |
| E324 SCHEMBL6354639 | 0.65 | ALDH1A1 (0.79) | PGRALDH1A1HSD17B10CYP3A4TDP1 | |
| SCHEMBL2395971 | 0.65 | PGR (0.52) | PGRALDH1A1HSD17B10CYP3A4TDP1 | |
| SCHEMBL2035899 | 0.64 | GAA (0.55) | ALDH1A1HSD17B10CYP3A4TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023235855-A1 | QUINOLINEAMINE ANTIDEGRADANT COMPOUNDS AND USES THEREOF | FLEXSYS AMERICA L.P. (US) | 2023-12-07 | — | — | WO | disclosed |