Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | YTHDF3 | Q7Z739 | 1/20 | 0.42 |
| ▸ | YTHDF1 | Q9BYJ9 | 1/20 | 0.42 |
| ▸ | YTHDF2 | Q9Y5A9 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.36 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 4/20 | 0.34 |
| ▸ | JAK1 | P23458 | 4/20 | 0.34 |
| ▸ | JAK3 | P52333 | 4/20 | 0.34 |
| ▸ | TYK2 | P29597 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1362732 | 0.73 | GPR84 (0.53) | GPR84YTHDF3YTHDF1YTHDF2CA1 | |
| SCHEMBL28818278 | 0.71 | GPR84 (0.51) | GPR84YTHDF3YTHDF1YTHDF2CA1 | |
| SCHEMBL10095166 | 0.64 | GPR84 (0.53) | GPR84CA1ALDH1A1 | |
| SCHEMBL22239460 | 0.63 | YTHDF2 (0.81) | GAAKDM4CYTHDF3YTHDF1YTHDF2 | |
| SCHEMBL12612092 | 0.63 | YTHDF2 (0.81) | GAAKDM4CYTHDF3YTHDF1YTHDF2 | |
| SCHEMBL14656172 | 0.61 | GPR84 (0.69) | GPR84CA1ALDH1A1 | |
| SCHEMBL4485887 | 0.58 | HRH4 (0.44) | GAAMEN1KMT2AJAK2JAK1 | |
| SCHEMBL60308 | 0.57 | — | — | |
| Cyclopropane SCHEMBL27480802 | 0.57 | CA1 (0.44) | GPR84KDM4CYTHDF3YTHDF1YTHDF2 | |
| SCHEMBL22837457 | 0.57 | ADH1A (0.46) | GAAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1031641-C | Process for preparing 8-substituted xanthine | BEECHAM WUELFING GMBH & CO KG (DE) | 1996-04-24 | — | — | CN | disclosed |
| CN-1047502-A | The preparation method of 8-substituted xanthine | BEECHAM WUELFING GMBH & CO KG (DE) | 1990-12-05 | — | — | CN | disclosed |