Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.43 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.43 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.43 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27312349 | 0.91 | HTT (0.56) | HTTSMN1; SMN2NPSR1MAPTLMNA | |
| SCHEMBL30877035 | 0.81 | NAMPT (0.47) | KDM4EALDH1A1RORCTACR1NAMPT | |
| SCHEMBL27312087 | 0.79 | LMNA (0.60) | HTTSMN1; SMN2LMNAKDM4EALDH1A1 | |
| SCHEMBL27312340 | 0.78 | HTT (0.50) | HTTSMN1; SMN2NPSR1MAPTLMNA | |
| SCHEMBL28035458 | 0.78 | HTT (0.63) | HTTSMN1; SMN2NPSR1MAPTLMNA | |
| SCHEMBL27312118 | 0.77 | LMNA (0.54) | HTTSMN1; SMN2MAPTLMNAGAA | |
| SCHEMBL27312351 | 0.77 | ALDH1A1 (0.59) | HTTSMN1; SMN2NPSR1MAPTLMNA | |
| SCHEMBL27312347 | 0.76 | CA2 (0.55) | HTTSMN1; SMN2MAPTLMNAKDM4E | |
| SCHEMBL27313733 | 0.75 | CA12 (0.53) | HTTSMN1; SMN2MAPTLMNAALDH1A1 | |
| SCHEMBL30877030 | 0.74 | POLB (0.47) | HTTSMN1; SMN2NPSR1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024091450-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-05-02 | — | — | WO | disclosed |