Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Tetrabuthylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 4/20 | 0.86 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.58 |
| ▸ | APAF1 | O14727 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrabuthylammonium SCHEMBL28870345 | 1.00 | SLC22A1 (0.86) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL28143245 | 0.97 | SLC22A1 (0.80) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL27783348 | 0.97 | SLC22A1 (0.80) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL28183153 | 0.97 | SLC22A1 (0.80) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL28294190 | 0.96 | SLC22A1 (0.92) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL4260120 | 0.96 | SLC22A1 (0.92) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL21980 | 0.96 | SLC22A1 (0.92) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL29026657 | 0.96 | SLC22A1 (0.92) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL28038501 | 0.94 | SLC22A1 (0.75) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL23647351 | 0.93 | SLC22A1 (0.86) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 299 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110498883-A | A kind of preparation method of cation ester group Concentrated Emulsion Polymerization object | UNIV HUBEI TECHNOLOGY | 2019-11-26 | — | — | CN | claimed |
| CN-110465326-A | A kind of method of modifying for ethyl alcohol and benzene alkylation reaction ZSM-11 molecular sieve catalyst | DALIAN INST CHEM & PHYSICS CAS | 2019-11-19 | — | — | CN | claimed |
| CN-110128555-A | The preparation method of Cellulose nanocrystal body | 广西大学 | 2019-08-16 | — | — | CN | claimed |
| CN-110093607-A | Deburring liquid, preparation method and application for lead frame | 上海新阳半导体材料股份有限公司 | 2019-08-06 | — | — | CN | claimed |
| CN-106914274-B | With nanoscale twins from the multi-stage porous Titanium Sieve Molecular Sieve and its preparation method and application of delaminated structure | 西北大学 | 2019-08-02 | — | — | CN | claimed |
| CN-110038488-A | A method of hydrogen is produced using organic solid castoff | 南开大学 | 2019-07-23 | — | — | CN | claimed |
| CN-110004449-A | Cleaning solution, preparation method and application after stable type chemically mechanical polishing | 上海新阳半导体材料股份有限公司 | 2019-07-12 | — | — | CN | claimed |
| CN-106188549-B | A kind of polyphosphate oligomer fire retardant and preparation method thereof | 中蓝晨光化工研究设计院有限公司 | 2019-07-12 | — | — | CN | claimed |
| CN-109988675-A | Cleaning solution, preparation method and application after long-acting type chemically mechanical polishing | 上海新阳半导体材料股份有限公司 | 2019-07-09 | — | — | CN | claimed |
| CN-109988676-A | A kind of cleaning solution, preparation method and application | 上海新阳半导体材料股份有限公司 | 2019-07-09 | — | — | CN | claimed |
| CN-102558563-A | Preparation method for high-viscosity 107 glue | JIANGXI STAR FIRE SILICONE FACTORY OF BLUESTAR NEW CHEM MAT CO LTD | 2012-07-11 | — | — | CN | claimed |
| CN-101928399-A | Preparation method for 107 silicon rubber with controllable viscosity | ZHEJIANG TRANSIT FLUORINE SILICON MATERIAL CO LTD | 2010-12-29 | — | — | CN | claimed |
| CN-101880396-A | Preparation method of organic silicon rubber for encapsulating LED being convenient for vacuum defoamation | UNIV HANGZHOU NORMAL | 2010-11-10 | — | — | CN | claimed |
| CN-101328153-B | Preparation of tris(tri-bromophenoxy) triazine by nonsolvent method | HANGZHOU JLS FLAME RETARDANTS CHEMICAL CO LTD | 2010-07-28 | — | — | CN | claimed |
| CN-101781328-A | Preparation method of cyclosiloxane | SHANDONG JIULONG POLYMER CO LT | 2010-07-21 | — | — | CN | claimed |
| CN-100532367-C | High stack-density sheet structural melamine cyanurate and production method and application for flame-resistant material | HANGZHOU JLS FLAME RETARDANTS (CN) | 2009-08-26 | — | — | CN | claimed |
| CN-101328153-A | Preparation of tris(tri-bromophenoxy) triazine by nonsolvent method | HANGZHOU JLS FLAME RETARDANTS (CN) | 2008-12-24 | — | — | CN | claimed |
| CN-101037417-A | High stack-density sheet structural melamine cyanurate and production method and application for flame-resistant material | HANGZHOU JLS FLAME RETARDANTS (CN) | 2007-09-19 | — | — | CN | claimed |
| CN-1796441-A | Trapezoidal organic poly sesquisiloxane and preparation method | CHINESE ACAD INST CHEMISTRY (CN) | 2006-07-05 | — | — | CN | claimed |
| CN-1139430-C | Zeolite catalyst for directly synthesizing aromatic hydrocarbon by using methane and its preparation method | 吉林大学 | 2004-02-25 | — | — | CN | claimed |