Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCPS | Q96C86 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | MPO | P05164 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 2/20 | 0.50 |
| ▸ | CASP7 | P55210 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | NQO2 | P16083 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27816217 | 0.84 | APP (0.58) | DCPSAPPALDH1A1HSD17B10HPGD | |
| SCHEMBL4162349 | 0.80 | MPO (0.44) | DCPSAPPMPOLTB4R | |
| SCHEMBL4572143 | 0.79 | NUDT1 (0.58) | DCPSAPPALDH1A1HSD17B10HPGD | |
| SCHEMBL787604 | 0.79 | KDM4E (0.57) | APPALDH1A1HSD17B10HPGDKDM4E | |
| SCHEMBL28211667 | 0.79 | L3MBTL1 (0.60) | ALDH1A1HSD17B10HPGDCYP1A2KDM4E | |
| SCHEMBL31682474 | 0.79 | L3MBTL1 (0.60) | ALDH1A1HSD17B10HPGDCYP1A2KDM4E | |
| SCHEMBL28175543 | 0.79 | KMT2A (0.62) | ALDH1A1HSD17B10HPGDCYP1A2KDM4E | |
| SCHEMBL27670797 | 0.78 | DCPS (0.47) | DCPSAPPALDH1A1HSD17B10HPGD | |
| SCHEMBL16943987 | 0.76 | MPO (0.53) | DCPSCYP1A2MPOLTB4R | |
| SCHEMBL2420150 | 0.74 | MPO (0.48) | DCPSAPPCYP1A2MPOLTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1049498-A | 2,4-diamino-5-replacement-6-(N-replaces benzyl amino) quinazoline derivant is synthetic | SHANGHAI INST PHARM INDUSTRY (CN) | 1991-02-27 | — | — | CN | claimed |
| CN-86100512-A | 2 of antitumor action is arranged, and 4-diamino-6-(N-methyl or formyl radical-replacement benzyl amino) quinoline derivatives is synthetic | — | 1987-09-02 | — | — | CN | claimed |
| CN-1049498-A | 2,4-diamino-5-replacement-6-(N-replaces benzyl amino) quinazoline derivant is synthetic | SHANGHAI INST PHARM INDUSTRY (CN) | 1991-02-27 | — | — | CN | disclosed |
| CN-86100512-A | 2 of antitumor action is arranged, and 4-diamino-6-(N-methyl or formyl radical-replacement benzyl amino) quinoline derivatives is synthetic | — | 1987-09-02 | — | — | CN | disclosed |
| CN-86100512-A | 2 of antitumor action is arranged, and 4-diamino-6-(N-methyl or formyl radical-replacement benzyl amino) quinoline derivatives is synthetic | — | 1987-09-02 | — | — | CN | disclosed |