Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 5/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 5/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 5/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27313609 | 0.80 | KDM4E (0.38) | RAPGEF4CSNK2A2CSNK2BCSNK2A1NUDT1 | |
| SCHEMBL24682831 | 0.80 | — | — | |
| SCHEMBL23241836 | 0.75 | AR (0.35) | RAPGEF4CSNK2A2CSNK2BCSNK2A1NUDT1 | |
| SCHEMBL16126075 | 0.71 | CYP2A6 (0.42) | POLB | |
| SCHEMBL28569245 | 0.69 | CSNK2A2 (0.37) | ATMCSNK2A2CSNK2BCSNK2A1TP53 | |
| SCHEMBL11538950 | 0.68 | ALDH1A1 (0.37) | CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL11549214 | 0.68 | PSMB5 (0.44) | CSNK2A2CSNK2BCSNK2A1NUDT1TP53 | |
| SCHEMBL16707578 | 0.67 | CSNK2A2 (0.48) | ATMRAPGEF4CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL24912992 | 0.67 | PTPN1 (0.43) | CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL5373635 | 0.67 | PTPN1 (0.54) | CSNK2A2CSNK2BCSNK2A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240208945-A1 | 6-CARBAMATE SUBSTITUTED HETEROARYL RING DERIVATIVES | MEDSHINE DISCOVERY INC. (CN) | 2024-06-27 | — | — | US | disclosed |
| US-20240208945-A1 | 6-CARBAMATE SUBSTITUTED HETEROARYL RING DERIVATIVES | MEDSHINE DISCOVERY INC. (CN) | 2024-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240208945-A1 | 6-CARBAMATE SUBSTITUTED HETEROARYL RING DERIVATIVES | CYP3A7, UGT2B7, CYP51A1 | ATM 4594/4885RAPGEF4 2676/4885CSNK2A2 1052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.