Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 4/20 | 0.66 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.55 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.55 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.46 |
| ▸ | GPR183 | P32249 | 4/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | OXTR | P30559 | 1/20 | 0.40 |
| ▸ | KLK3 | P07288 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL71905 | 0.80 | NNMT (1.00) | NNMTMAOAMAOBMKNK1MKNK2 | |
| SCHEMBL29975550 | 0.80 | NNMT (1.00) | NNMTMAOAMAOBMKNK1MKNK2 | |
| Hydrochloric Acid SCHEMBL5013391 | 0.78 | NNMT (0.96) | NNMTMAOAMAOBMKNK1MKNK2 | |
| Hydrochloric Acid SCHEMBL6234386 | 0.78 | NNMT (0.96) | NNMTMAOAMAOBMKNK1MKNK2 | |
| SCHEMBL17339656 | 0.78 | NNMT (0.70) | NNMTMAOAMAOBMKNK1MKNK2 | |
| SCHEMBL30475723 | 0.78 | NNMT (0.70) | NNMTMAOAMAOBMKNK1MKNK2 | |
| SCHEMBL17339657 | 0.76 | NNMT (0.54) | NNMTMAOAMAOBMKNK1MKNK2 | |
| SCHEMBL4582780 | 0.76 | NNMT (0.58) | NNMTMAOAMAOBMKNK1MKNK2 | |
| SCHEMBL4582774 | 0.76 | NNMT (0.58) | NNMTMAOAMAOBMKNK1MKNK2 | |
| SCHEMBL18228074 | 0.76 | NNMT (0.72) | NNMTMAOAMAOBMKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024086361-A1 | MOLECULAR GLUE DEGRADER COMPOUNDS AND USES THEREOF | NOVARTIS AG (CH) | 2024-04-25 | — | — | WO | disclosed |