SCHEMBL273144

SCHEMBL273144

NP(=O)(O)NN1CCOCC1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 1/20 0.47
MMP3 P08254 1/20 0.47
MMP8 P22894 1/20 0.47
ANPEP P15144 1/20 0.40
CA12 O43570 3/20 0.38
CA1 P00915 3/20 0.38
CA9 Q16790 3/20 0.38
CA2 P00918 2/20 0.38
GAA P10253 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
CYP2D6 P10635 1/20 0.36
MEN1 O00255 1/20 0.34
TP53 P04637 1/20 0.34
KMT2A Q03164 1/20 0.34
HTT P42858 1/20 0.34
ALPG P10696 1/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1246277 0.82 MMP1 (0.50) MMP1MMP3MMP8ANPEPCA12
SCHEMBL32685957 0.78 MMP1 (0.38) MMP1MMP3MMP8ANPEPCA12
SCHEMBL9346545 0.73 MMP1 (0.40) MMP1MMP3MMP8CA12CA1
SCHEMBL1246279 0.70 MMP1 (0.46) MMP1MMP3MMP8ANPEPCA12
SCHEMBL5691755 0.70 ANPEP (0.44) MMP1MMP3MMP8ANPEPCA12
Phosphoramidic Acid SCHEMBL29069931 0.68 MMP1 (0.45) MMP1MMP3MMP8ANPEPCA12
SCHEMBL10527462 0.68 PHGDH (0.39) CA12SMN1; SMN2KMT2A
SCHEMBL3363445 0.68 ALDH1A1 (0.38) MMP1MMP3MMP8SMN1; SMN2CYP2D6
SCHEMBL1615661 0.65 MMP1 (0.42) MMP1MMP3MMP8ANPEPCA12
SCHEMBL329843 0.64 MMP1 (0.50) MMP1MMP3MMP8ANPEPCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3238737-B1 MEANS AND METHODS FOR COUNTERACTING MUSCLE DISORDERS ACADEMISCH ZIEKENHUIS LEIDEN (NL) 2022-04-06 EP claimed
US-11274299-B2 Methods and means for treating DNA repeat instability associated genetic disorders VICO THERAPEUTICS B.V. (NL) 2022-03-15 US claimed
US-20200140857-A1 Methods and means for treating DNA repeat instability associated genetic disorders VICO THERAPEUTICS B.V. (NL) 2020-05-07 US claimed
EP-3265581-B1 SIMULTANEOUS DETECTION OF OLIGONUCLEOTIDES, A KIT AND A USE RELATED THERETO AXOLABS GMBH (DE) 2019-05-01 EP claimed
EP-2614827-B1 Means and methods for counteracting muscle disorders ACADEMISCH ZIEKENHUIS LEIDEN (NL) 2017-06-28 EP claimed
EP-2426203-B1 Agents useful in treating facioscapulohumeral muscular dystrophy Université de Mons (BE) 2016-07-13 EP claimed
EP-2421971-B1 OLIGONUCLEOTIDE COMPRISING AN INOSINE FOR TREATING DMD BIOMARIN TECHNOLOGIES B V (NL) 2016-07-06 EP claimed
EP-2203173-B1 MEANS AND METHODS FOR COUNTERACTING MUSCLE DISORDERS ACADEMISCH ZIEKENHUIS LEIDEN (NL) 2015-12-23 EP claimed
EP-2331950-B1 NANOSTRUCTURED MICROELECTRODES AND BIOSENSING DEVICES INCORPORATING THE SAME UNIV TORONTO (CA) 2014-07-23 EP claimed
EP-1606407-B1 MODULATION OF EXON RECOGNITION IN PRE-MRNA BY INTERFERING WITH THE SECONDARY RNA STRUCTURE ACADEMISCH ZIEKENHUIS LEIDEN (NL) 2013-12-18 EP claimed
US-20110092380-A1 IMPROVED MOLECULAR-BIOLOGICAL PROCESSING EQUIPMENT FEBIT HOLDING GMBH (DE) 2011-04-21 US claimed
EP-2004156-B1 COMPOSITIONS FOR TRANSFECTION OF OLIGONUCLEOTIDES ACTIVE FOR GENE SILENCING AND THEIR BIOLOGICAL AND THERAPEUTICAL APPLICATIONS POLYPLUS TRANSFECTION SA (FR) 2011-01-26 EP claimed
WO-2005048944-A2 ACTIVATABLE PHOTODYNAMIC THERAPY AGENTS UNIVERSITY OF PENNSYLVANIA (US) 2005-06-02 WO claimed
WO-2003038122-A2 ASYMMETRICAL PROBES FEBIT AG (DE) 2003-05-08 WO claimed
US-12595486-B2 Aptamers for personal health care applications THE PROCTER & GAMBLE COMPANY (US) 2026-04-07 US disclosed
US-12584135-B2 Aptamers for personal health care applications THE PROCTER & GAMBLE COMPANY (US) 2026-03-24 US disclosed
US-12584137-B2 Aptamers for personal health care applications THE PROCTER & GAMBLE COMPANY (US) 2026-03-24 US disclosed
EP-1185303-A1 INHIBITION OF GASTRIC ACID PRODUCTION AND/OR SECRETION Tachas, George (AU) 2002-03-13 EP disclosed
WO-2002009509-A2 INHIBITION OF GENE EXPRESSION USING POLYNUCLEOTIDE ANALOGUES REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2002-02-07 WO disclosed
WO-2000071164-A1 INHIBITION OF GASTRIC ACID PRODUCTION AND/OR SECRETION TACHAS GEORGE (AU) 2000-11-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12584135-B2 Aptamers for personal health care applications ICAM1, VCAM1, EPCAM MMP1 3579/4885MMP3 2294/4885MMP8 3099/4885
US-12595486-B2 Aptamers for personal health care applications HAVCR2, EPCAM, ICAM1 MMP1 4358/4885MMP3 2295/4885MMP8 3097/4885
US-12584137-B2 Aptamers for personal health care applications HAVCR2, LDLR, ICAM1 MMP1 4298/4885MMP3 2224/4885MMP8 2803/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.