SCHEMBL1246277

SCHEMBL1246277

O=P(O)(O)NN1CCOCC1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 1/20 0.50
MMP3 P08254 1/20 0.50
MMP8 P22894 1/20 0.50
HTT P42858 1/20 0.41
CA12 O43570 3/20 0.40
CA1 P00915 3/20 0.40
CA9 Q16790 3/20 0.40
CA2 P00918 2/20 0.40
GAA P10253 1/20 0.38
ANPEP P15144 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
CYP2D6 P10635 1/20 0.38
MEN1 O00255 1/20 0.37
TP53 P04637 1/20 0.37
KMT2A Q03164 1/20 0.37
PKM P14618 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL273144 0.82 MMP1 (0.47) MMP1MMP3MMP8HTTCA12
SCHEMBL975100 0.77 MMP1 (0.42) MMP1MMP3MMP8HTTCA12
SCHEMBL9346545 0.76 MMP1 (0.40) MMP1MMP3MMP8HTTCA12
SCHEMBL32685957 0.73 MMP1 (0.38) MMP1MMP3MMP8HTTCA12
SCHEMBL5691755 0.73 ANPEP (0.44) MMP1MMP3MMP8HTTCA12
SCHEMBL3363445 0.71 ALDH1A1 (0.38) MMP1MMP3MMP8HTTSMN1; SMN2
SCHEMBL329843 0.67 MMP1 (0.50) MMP1MMP3MMP8CA12CA1
SCHEMBL2974382 0.67 MMP1 (0.50) MMP1MMP3MMP8CA12CA1
SCHEMBL8009456 0.66
Hydrochloric Acid SCHEMBL11081547 0.65 MMP1 (0.48) MMP1MMP3MMP8CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 331 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3850099-B1 MICRORNA INHIBITORS FOR USE IN TREATING METABOLIC DISEASES HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM GESUNDHEIT & UMWELT GMBH (DE) 2025-09-03 EP claimed
US-20240060068-A1 POLY-MORPHOLINO OLIGONUCLEOTIDE GAPMERS EISAI R&D MANAGEMENT CO., LTD. (JP) 2024-02-22 US claimed
CN-117120456-A Poly-morpholino oligonucleotide gap body 卫材R&D管理有限公司 2023-11-24 CN claimed
EP-4259798-A1 POLY-MORPHOLINO OLIGONUCLEOTIDE GAPMERS Eisai R&D Management Co., Ltd. (JP) 2023-10-18 EP claimed
WO-2022125987-A1 POLY-MORPHOLINO OLIGONUCLEOTIDE GAPMERS EISAI R&D MANAGEMENT CO., LTD. (JP) 2022-06-16 WO claimed
US-12595486-B2 Aptamers for personal health care applications THE PROCTER & GAMBLE COMPANY (US) 2026-04-07 US disclosed
US-20260085087-A1 CHEMICAL COMPOUND COMPRISING A TRIAZINE GROUP AND METHOD FOR PRODUCING SAME KUPRYUSHKIN MAXIM SERGEEVICH (RU) 2026-03-26 US disclosed
US-12584137-B2 Aptamers for personal health care applications THE PROCTER & GAMBLE COMPANY (US) 2026-03-24 US disclosed
US-12584136-B2 Aptamers for personal health care applications THE PROCTER & GAMBLE COMPANY (US) 2026-03-24 US disclosed
US-12584135-B2 Aptamers for personal health care applications THE PROCTER & GAMBLE COMPANY (US) 2026-03-24 US disclosed
US-12359205-B2 Aptamers for personal health care applications THE PROCTER & GAMBLE COMPANY (US) 2025-07-15 US disclosed
EP-3664776-B1 APTAMERS FOR CONSUMER PRODUCT COMPOSITIONS PROCTER & GAMBLE (US) 2025-05-14 EP disclosed
US-6743905-B2 BIOPOLYMER FOR USE IN THE DETECTION OF PREERENTIAL SEQUENCES IN SAMPLE APPLERA CORPORATION 2004-06-01 US disclosed
EP-1334110-A2 METHODS FOR ISOLATING ONE STRAND OF A DOUBLE-STRANDED NUCLEIC ACID Applera Corporation (US) 2003-08-13 EP disclosed
US-20030148277-A1 Methods for isolating one strand of a double-stranded nucleic acid APPLIED BIOSYSTEMS, LLC 2003-08-07 US disclosed
US-20020182602-A1 Mobility-modified nucleobase polymers and methods of using same APPLIED BIOSYSTEMS, INC. 2002-12-05 US disclosed
WO-2002010182-A2 METHODS FOR ISOLATING ONE STRAND OF A DOUBLE-STRANDED NUCLEIC ACID APPLERA CORPORATION (US) 2002-02-07 WO disclosed
EP-0605582-A1 PHOSPHORAMIDATE ANALOGS OF 5-FLUORO-2'-DEOXYURIDINE THE UNIVERSITY OF ROCHESTER (US) 1994-07-13 EP disclosed
US-5233031-A Antitumor, anticarcinogenic agents UNIVERSITY OF ROCHESTER (US) 1993-08-03 US disclosed
WO-1993006120-A1 PHOSPHORAMIDATE ANALOGS OF 5-FLUORO-2'-DEOXYURIDINE UNIVERSITY OF ROCHESTER (US) 1993-04-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260085087-A1 CHEMICAL COMPOUND COMPRISING A TRIAZINE GROUP AND METHOD FOR PRODUCING SAME NSUN2, POLM, SSU72 MMP1 4721/4885MMP3 4235/4885MMP8 3882/4885
US-20020182602-A1 Mobility-modified nucleobase polymers and methods of using same PCNA, PNKP, SAMHD1 MMP1 1888/4885MMP3 1693/4885MMP8 768/4885
US-12584136-B2 Aptamers for personal health care applications HAVCR2, LDLR, ICAM1 MMP1 4300/4885MMP3 3143/4885MMP8 3667/4885
US-20240060068-A1 POLY-MORPHOLINO OLIGONUCLEOTIDE GAPMERS RNMT, GAP43, MCTS1 MMP1 3535/4885MMP3 3632/4885MMP8 3892/4885
US-12584135-B2 Aptamers for personal health care applications ICAM1, VCAM1, EPCAM MMP1 3579/4885MMP3 2294/4885MMP8 3099/4885
US-12595486-B2 Aptamers for personal health care applications HAVCR2, EPCAM, ICAM1 MMP1 4358/4885MMP3 2295/4885MMP8 3097/4885
US-12584137-B2 Aptamers for personal health care applications HAVCR2, LDLR, ICAM1 MMP1 4298/4885MMP3 2224/4885MMP8 2803/4885
US-20030148277-A1 Methods for isolating one strand of a double-stranded nucleic acid POLRMT, POLN, ADAR MMP1 3912/4885MMP3 1840/4885MMP8 1510/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.