Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27316051 | 0.82 | DUT (0.33) | DUT | |
| SCHEMBL30848887 | 0.77 | DUT (0.31) | DUT | |
| SCHEMBL11580466 | 0.73 | DUT (0.42) | DUT | |
| SCHEMBL5346493 | 0.68 | ALDH1A1 (0.41) | DUT | |
| SCHEMBL735156 | 0.68 | TSHR (0.32) | — | |
| SCHEMBL14855784 | 0.67 | PSMB1 (0.42) | — | |
| SCHEMBL23355821 | 0.66 | CHKA (0.44) | — | |
| SCHEMBL27316114 | 0.66 | MGLL (0.33) | — | |
| SCHEMBL27316234 | 0.66 | — | — | |
| SCHEMBL12311332 | 0.66 | NPC1 (0.36) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587017-A2 | HYDROXYLAMINE-BASED EGFR INHIBITORS FOR TREATMENT OF CANCER WITH BRAIN METASTASES | University of Georgia Research Foundation, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| CN-119894510-A | Hydroxylamine-based EGFR inhibitors for the treatment of brain metastasis | 乔治亚大学研究基金会 | 2025-04-25 | — | — | CN | disclosed |
| WO-2024059668-A2 | HYDROXYLAMINE-BASED EGFR INHIBITORS FOR TREATMENT OF CANCER WITH BRAIN METASTASES | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2024-03-21 | — | — | WO | disclosed |
| WO-2024059668-A2 | HYDROXYLAMINE-BASED EGFR INHIBITORS FOR TREATMENT OF CANCER WITH BRAIN METASTASES | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2024-03-21 | — | — | WO | disclosed |