Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 11/20 | 0.60 |
| ▸ | CYP11B2 | P19099 | 11/20 | 0.60 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27306308 | 0.88 | CYP11B1 (0.52) | CYP11B1CYP11B2IDO1HSP90AA1HSP90AB1 | |
| SCHEMBL9092542 | 0.86 | CYP11B1 (0.54) | CYP11B1CYP11B2IDO1HSP90AA1HSP90AB1 | |
| SCHEMBL27388451 | 0.86 | CYP11B1 (0.54) | CYP11B1CYP11B2IDO1HSP90AA1HSP90AB1 | |
| SCHEMBL6774868 | 0.78 | CYP11B1 (0.54) | CYP11B1CYP11B2IDO1HSP90AA1HSP90AB1 | |
| SCHEMBL15458790 | 0.78 | CYP11B1 (0.57) | CYP11B1CYP11B2IDO1HSP90AA1HSP90AB1 | |
| SCHEMBL6504426 | 0.77 | CYP11B1 (0.61) | CYP11B1CYP11B2IDO1FNTAFNTB | |
| SCHEMBL8297235 | 0.77 | CYP11B1 (0.61) | CYP11B1CYP11B2IDO1FNTAFNTB | |
| SCHEMBL2789863 | 0.77 | CYP11B1 (0.76) | CYP11B1CYP11B2IDO1HPGDSFNTA | |
| SCHEMBL11392729 | 0.76 | CYP11B1 (0.70) | CYP11B1CYP11B2IDO1MAPTMAPK1 | |
| SCHEMBL27304028 | 0.76 | RAB9A (0.48) | CYP11B1CYP11B2HSP90AA1HSP90AB1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1036993-C | Aromatase inhibiting 4(5)-imidazoles | FARMOS OY (FI) | 1998-01-14 | — | — | CN | disclosed |
| CN-1033995-A | 4 (5)-imidazoles that suppress aromatase enzyme | FARMOS OY (FI) | 1989-07-19 | — | — | CN | disclosed |