Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 5/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27316522 | 0.88 | CYP11B1 (0.60) | CYP11B1CYP11B2HSP90AA1HSP90AB1IDO1 | |
| SCHEMBL9092542 | 0.85 | CYP11B1 (0.54) | CYP11B1CYP11B2HSP90AA1HSP90AB1IDO1 | |
| SCHEMBL27388451 | 0.85 | CYP11B1 (0.54) | CYP11B1CYP11B2HSP90AA1HSP90AB1IDO1 | |
| SCHEMBL6776094 | 0.79 | CYP11B1 (0.62) | CYP11B1CYP11B2IDO1ALDH1A1TSHR | |
| SCHEMBL16380792 | 0.78 | CYP11B1 (0.57) | CYP11B1CYP11B2LMNACYP1A2CYP3A4 | |
| SCHEMBL6774868 | 0.77 | CYP11B1 (0.54) | CYP11B1CYP11B2HSP90AA1HSP90AB1IDO1 | |
| SCHEMBL9642301 | 0.77 | CYP11B1 (0.77) | CYP11B1CYP11B2IDO1 | |
| SCHEMBL9092959 | 0.77 | CYP11B1 (0.52) | CYP11B1CYP11B2HSP90AA1HSP90AB1IDO1 | |
| SCHEMBL15458790 | 0.77 | CYP11B1 (0.57) | CYP11B1CYP11B2CYP1A2CYP3A4HSP90AA1 | |
| SCHEMBL9123088 | 0.75 | CYP11B1 (0.67) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1036993-C | Aromatase inhibiting 4(5)-imidazoles | FARMOS OY (FI) | 1998-01-14 | — | — | CN | disclosed |
| CN-1033995-A | 4 (5)-imidazoles that suppress aromatase enzyme | FARMOS OY (FI) | 1989-07-19 | — | — | CN | disclosed |