Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 11/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 11/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9092542 | 0.91 | CYP11B1 (0.54) | CYP11B1CYP11B2IDO1HSP90AA1HSP90AB1 | |
| SCHEMBL27316522 | 0.86 | CYP11B1 (0.60) | CYP11B1CYP11B2IDO1HSP90AA1HSP90AB1 | |
| SCHEMBL27306308 | 0.85 | CYP11B1 (0.52) | CYP11B1CYP11B2IDO1HSP90AA1HSP90AB1 | |
| SCHEMBL6774868 | 0.83 | CYP11B1 (0.54) | CYP11B1CYP11B2IDO1HSP90AA1HSP90AB1 | |
| SCHEMBL15458790 | 0.82 | CYP11B1 (0.57) | CYP11B1CYP11B2IDO1HSP90AA1HSP90AB1 | |
| SCHEMBL9092959 | 0.79 | CYP11B1 (0.52) | CYP11B1CYP11B2IDO1HSP90AA1HSP90AB1 | |
| SCHEMBL27388454 | 0.79 | CYP11B1 (0.50) | CYP11B1CYP11B2IDO1HSP90AA1HSP90AB1 | |
| Trifluoroacetic Acid SCHEMBL5880540 | 0.78 | CYP11B1 (0.48) | CYP11B1CYP11B2IDO1HSP90AA1HSP90AB1 | |
| SCHEMBL10790711 | 0.76 | CYP11B1 (0.54) | CYP11B1CYP11B2IDO1HSP90AA1HSP90AB1 | |
| SCHEMBL8388778 | 0.75 | CYP11B1 (0.59) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1068592-C | Imidazole derivatives having affinity for alpha 2 receptors activity | ORION YHTYMAE OY (FI) | 2001-07-18 | — | — | CN | disclosed |
| CN-1198741-A | Imidazole derivatives having affinity for alpha 2 receptor activity | ORION YHTYMAE OY (FI) | 1998-11-11 | — | — | CN | disclosed |