Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27300413 | 0.76 | CYP2C9 (0.41) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL27295071 | 0.76 | CYP2C9 (0.41) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL27295072 | 0.76 | CYP2C9 (0.41) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL27869836 | 0.74 | HSD11B1 (0.42) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL27389644 | 0.72 | DRD4 (0.41) | MEN1KMT2ACARM1PRMT6 | |
| SCHEMBL4918201 | 0.72 | DRD4 (0.41) | MEN1KMT2ACARM1PRMT6 | |
| Hydrochloric Acid SCHEMBL4917162 | 0.71 | DRD4 (0.41) | MEN1KMT2ACARM1PRMT6 | |
| SCHEMBL6065495 | 0.69 | NOS3 (0.46) | NOS1NOS2 | |
| SCHEMBL12262005 | 0.69 | NOS3 (0.46) | NOS1NOS2 | |
| SCHEMBL22185917 | 0.69 | NOS3 (0.46) | NOS1NOS2HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1045595-C | Process for the preparation of the intermediates used in the synthesis of 3-aminopiperidine derivatives | PFIZER (US) | 1999-10-13 | — | — | CN | disclosed |
| CN-1035944-C | 3-aminopiperidine derivatives and related nitrogen-containing heterocyclic compounds | PFIZER (US) | 1997-09-24 | — | — | CN | disclosed |
| CN-1087083-A | The intermediates preparation of synthetic 3-amino piperidine derivatives | PFIZER (US) | 1994-05-25 | — | — | CN | disclosed |
| CN-1053060-A | 3-aminopiperidine derivatives and related nitrogen-containing heterocycles | PFIZER (US) | 1991-07-17 | — | — | CN | disclosed |