Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.35 |
| ▸ | MEN1 | O00255 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27321096 | 0.91 | KMT2A (0.35) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL31534075 | 0.85 | ADRA2A (0.38) | ADRA2AADRA2BADRA2CHTR7HTR2B | |
| SCHEMBL31534087 | 0.85 | LMNA (0.40) | KMT2AMEN1MAPTSMN1; SMN2LMNA | |
| SCHEMBL27320013 | 0.82 | HTR6 (0.46) | ADRA2AADRA2BADRA2CHTR7HTR2B | |
| SCHEMBL31534054 | 0.82 | HTR6 (0.46) | ADRA2AADRA2BADRA2CHTR7HTR2B | |
| SCHEMBL30867164 | 0.76 | IP6K1 (0.42) | HTR6KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL27319530 | 0.76 | IP6K1 (0.42) | HTR6KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL30867146 | 0.75 | KMT2A (0.36) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL27321109 | 0.75 | KMT2A (0.36) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL27321147 | 0.75 | MPO (0.37) | KMT2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119948035-A | Compounds useful for modulating AhR signaling | 捷豹治疗有限公司 | 2025-05-06 | — | — | CN | disclosed |
| WO-2024076300-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2024-04-11 | — | — | WO | disclosed |