Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27320131 | 0.86 | ALDH1A1 (0.41) | HRH3CNR2KCNH2KMT2AMAP4K4 | |
| SCHEMBL27320556 | 0.84 | HRH3 (0.36) | HRH3CNR2KCNH2KMT2AMAP4K4 | |
| SCHEMBL31413473 | 0.82 | PIK3CD (0.38) | HRH3CNR2KCNH2PIK3CDPIK3CA | |
| SCHEMBL27153214 | 0.82 | PIK3CD (0.38) | HRH3CNR2KCNH2PIK3CDPIK3CA | |
| SCHEMBL27320181 | 0.80 | HRH3 (0.49) | HRH3CNR2KCNH2KMT2APOLB | |
| SCHEMBL27320705 | 0.80 | ALDH1A1 (0.39) | HRH3MAP4K4MCHR1SMN1; SMN2 | |
| SCHEMBL27320489 | 0.75 | HSP90AB1 (0.42) | HRH3PIK3CDPIK3CALRRK2 | |
| SCHEMBL27320336 | 0.73 | HRH3 (0.47) | HRH3KCNH2POLBSMN1; SMN2 | |
| SCHEMBL27320321 | 0.73 | ACHE (0.39) | HRH3KCNH2MAP4K4DRD2DRD4 | |
| SCHEMBL27318949 | 0.72 | HRH3 (0.57) | HRH3KCNH2KMT2AMEN1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024006881-A1 | WEE1 DEGRADING COMPOUNDS AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-01-04 | — | — | WO | disclosed |