SCHEMBL27323920

SCHEMBL27323920

COc1cccc(C(=O)C(C)=Cc2ccccc2)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.63
CES1 P23141 1/20 0.63
KMT2A Q03164 3/20 0.60
LMNA P02545 1/20 0.60
HTT P42858 1/20 0.60
MEN1 O00255 2/20 0.59
ALDH1A1 P00352 1/20 0.59
MAOB P27338 1/20 0.59
BCHE P06276 1/20 0.56
NPC1 O15118 4/20 0.54
RAB9A P51151 4/20 0.54
POLB P06746 1/20 0.52
PARP1 P09874 1/20 0.51
ABCG2 Q9UNQ0 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
MTNR1A P48039 2/20 0.50
MTNR1B P49286 2/20 0.50
MAPT P10636 1/20 0.49
KCNK3 O14649 1/20 0.49
KCNK9 Q9NPC2 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27301045 0.83 CES2 (0.64) CES2CES1KMT2AMEN1ALDH1A1
SCHEMBL18320865 0.82 CES2 (0.67) CES2CES1KMT2ALMNAHTT
SCHEMBL18320866 0.82 CES2 (0.67) CES2CES1KMT2ALMNAHTT
SCHEMBL9647505 0.81 CES2 (0.89) CES2CES1KMT2AMEN1ALDH1A1
SCHEMBL11407221 0.81 AKR1C3 (0.67) CES2CES1KMT2ALMNAHTT
SCHEMBL6064618 0.81 AKR1C3 (0.67) CES2CES1KMT2ALMNAHTT
SCHEMBL351852 0.81 AKR1C3 (0.67) CES2CES1KMT2ALMNAHTT
SCHEMBL30889666 0.80 AKR1C3 (0.53) KMT2ALMNAMEN1ALDH1A1NPC1
SCHEMBL2156482 0.79 CES2 (1.00) CES2CES1KMT2AMEN1ALDH1A1
SCHEMBL29610859 0.79 CES2 (1.00) CES2CES1KMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1036276-A Make the method for erect image and negative-appearing image with the static main leaf of photo-hardening DU PONT (US) 1989-10-11 CN disclosed