Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.67 |
| ▸ | CES2 | O00748 | 4/20 | 0.56 |
| ▸ | CES1 | P23141 | 4/20 | 0.56 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6064618 | 1.00 | AKR1C3 (0.67) | AKR1C3CES2CES1AKR1C1ALDH1A1 | |
| SCHEMBL11407221 | 1.00 | AKR1C3 (0.67) | AKR1C3CES2CES1AKR1C1ALDH1A1 | |
| SCHEMBL14033873 | 0.90 | AKR1C3 (0.55) | AKR1C3CES2CES1AKR1C1ALDH1A1 | |
| SCHEMBL7701390 | 0.89 | CES2 (0.60) | AKR1C3CES2CES1ALDH1A1KMT2A | |
| SCHEMBL7701386 | 0.89 | CES2 (0.60) | AKR1C3CES2CES1ALDH1A1KMT2A | |
| SCHEMBL20415255 | 0.87 | CES2 (0.58) | AKR1C3CES2CES1AKR1C1ALDH1A1 | |
| SCHEMBL27301045 | 0.84 | CES2 (0.64) | AKR1C3CES2CES1ALDH1A1KMT2A | |
| SCHEMBL30889666 | 0.84 | AKR1C3 (0.53) | AKR1C3AKR1C1ALDH1A1KMT2AMAPT | |
| Styrene SCHEMBL27578113 | 0.84 | ALDH1A1 (0.49) | AKR1C3CES2CES1AKR1C1ALDH1A1 | |
| SCHEMBL27588182 | 0.83 | CES2 (0.49) | AKR1C3CES2CES1AKR1C1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 472 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117567303-A | Chalcone Mannich base compound, pharmaceutical composition, preparation method and application thereof | 安徽中医药大学 | 2024-02-20 | — | — | CN | claimed |
| CN-115043720-B | Novel alpha-methyl chalcone compound and preparation method and application thereof | 新疆医科大学 | 2023-11-21 | — | — | CN | claimed |
| CN-115141621-A | Oil-based fracturing fluid, multi-stage fracturing method and method for online monitoring productivity of reservoir intervals | 中国石油化工股份有限公司 | 2022-10-04 | — | — | CN | claimed |
| CN-115043720-A | Novel alpha-methyl chalcone compound and preparation method and application thereof | 新疆医科大学 | 2022-09-13 | — | — | CN | claimed |
| CN-110433115-A | A kind of preparation of hydrosol eye cream | BEIJING XUANGUANG PULI BIOMEDICAL TECH DEVELOPMENT CO LTD | 2019-11-12 | — | — | CN | claimed |
| CN-110292547-A | Cosmetic composition and preparation method thereof and cosmetics with anti-blue light action | 广东丸美生物技术股份有限公司 | 2019-10-01 | — | — | CN | claimed |
| EP-2706981-B1 | COSMETIC COMPOSITIONS | MARY KAY INC (US) | 2019-09-04 | — | — | EP | claimed |
| CN-110169940-A | A kind of Biofibre facial mask Essence having thin face function, preparation method and the facial mask using Essence preparation | 广州市如馨化妆品有限公司 | 2019-08-27 | — | — | CN | claimed |
| CN-110063916-A | Can Vitamin K, dispel eye pouch and eyeprint composition | 丁蓉 | 2019-07-30 | — | — | CN | claimed |
| CN-109846815-A | A kind of potent anti-ageing eye essence cream | 广州曼知生物科技有限公司 | 2019-06-07 | — | — | CN | claimed |
| JP-2001526658-A | — | — | 2001-12-18 | — | — | JP | claimed |
| EP-1039874-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF ALOPECIA | Mann, Morris A. (US) | 2000-10-04 | — | — | EP | claimed |
| EP-0981339-A1 | USE OF A PHARMACEUTICAL COMPOSITION FOR TREATING AND/OR PREVENTING ISCHEMIA | Remacle, José (BE) | 2000-03-01 | — | — | EP | claimed |
| US-6030948-A | FOR TREATMENT OF ALOPECIA | REGENERX BIOPHARMACEUTICALS, INC. | 2000-02-29 | — | — | US | claimed |
| WO-1999032072-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF ALOPECIA | MANN MORRIS A (US) | 1999-07-01 | — | — | WO | claimed |
| EP-0691886-B1 | MICROCAPSULES WITH WALLS MADE OF CROSS-LINKED PLANT POLYPHENOLS, AND COMPOSITIONS CONTAINING SAME | CENTRE NAT RECH SCIENT (FR) | 1999-04-28 | — | — | EP | claimed |
| WO-1998051291-A1 | USE OF A PHARMACEUTICAL COMPOSITION FOR TREATING AND/OR PREVENTING ISCHEMIA | REMACLE JOSE (BE) | 1998-11-19 | — | — | WO | claimed |
| EP-0691886-A1 | MICROCAPSULES WITH WALLS MADE OF CROSS-LINKED PLANT POLYPHENOLS, AND COMPOSITIONS CONTAINING SAME | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1996-01-17 | — | — | EP | claimed |
| WO-1995021018-A1 | MICROCAPSULES WITH WALLS MADE OF CROSS-LINKED PLANT POLYPHENOLS, AND COMPOSITIONS CONTAINING SAME | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1995-08-10 | — | — | WO | claimed |
| EP-0224386-A2 | Use of ruscogenins in the treatment of prostate disorders | Fink GmbH (DE) | 1987-06-03 | — | — | EP | claimed |