SCHEMBL2732463

SCHEMBL2732463

CC(C)NCCc1c[nH]c2ccccc12

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 5/20 0.69
KDM4E B2RXH2 3/20 0.69
ALDH1A1 P00352 3/20 0.69
HTR1A P08908 3/20 0.69
HTT P42858 1/20 0.69
MC5R P33032 1/20 0.62
MC3R P41968 1/20 0.62
MC1R Q01726 1/20 0.62
MEN1 O00255 4/20 0.60
KMT2A Q03164 4/20 0.60
CYP1A2 P05177 2/20 0.60
TSHR P16473 2/20 0.60
LMNA P02545 1/20 0.60
PKM P14618 1/20 0.60
CYP2C19 P33261 1/20 0.60
BLM P54132 1/20 0.60
G6PD P11413 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
IDO1 P14902 1/20 0.56
HTR2C P28335 3/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30536673 1.00 HTR2A (0.69) HTR2AKDM4EALDH1A1HTR1AHTT
Bromide SCHEMBL26186699 0.98 HTR2A (0.67) HTR2AKDM4EALDH1A1HTR1AHTT
Hydrochloric Acid SCHEMBL26688729 0.98 HTR2A (0.67) HTR2AKDM4EALDH1A1HTR1AHTT
SCHEMBL19411654 0.91 KDM4E (0.61) HTR2AKDM4EALDH1A1HTR1AHTT
SCHEMBL3241389 0.88 HTR2A (0.61) HTR2AKDM4EALDH1A1HTR1AHTT
Fumaric Acid SCHEMBL26688720 0.88 HTR1A (0.64) HTR2AKDM4EALDH1A1HTR1AHTT
SCHEMBL21781048 0.88 KDM4E (0.65) HTR2AKDM4EALDH1A1HTR1AHTT
SCHEMBL11828168 0.86 HTR2A (0.64) HTR2AKDM4EALDH1A1HTR1AHTT
SCHEMBL13652758 0.85 KDM4E (0.61) HTR2AKDM4EALDH1A1HTR1AHTT
SCHEMBL15130901 0.85 KMT2A (0.74) HTR2AKDM4EALDH1A1HTR1AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4507692-A2 TRYPTAMINE DERIVATIVES Caamtech, Inc. (US) 2025-02-19 EP claimed
WO-2024107445-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES FREEDOM BIOSCIENCES, INC. (US) 2024-05-23 WO claimed
WO-2023225679-A2 N-ISOPROPYL TRYPTAMINES AND METHOD OF MAKING MONOALKYLATED AND DIALKYLATED TRYPTAMINE ANALOGS CAAMTECH, INC. (US) 2023-11-23 WO claimed
WO-2023201293-A2 TRYPTAMINE DERIVATIVES CAAMTECH, INC. (US) 2023-10-19 WO claimed
EP-4208177-A1 CELLULAR COMPOSITION FOR TREATMENT OF DISEASES, DISORDERS OR CONDITIONS AND METHOD OF USE Yztherapeutic Performance Ltd. (IL) 2023-07-12 EP claimed
WO-2021108911-A1 USE OF PSILOCIN, PSILOCYBIN OR ANALOGS THEREOF IN WEIGHT LOSS, TREATMENT OF OBESITY AND COMPULSIVE EATING DISORDER NEONMIND BIOSCIENCES INC. (CA) 2021-06-10 WO claimed
CN-112105734-A Method for producing tryptamine 新图集生物技术有限责任公司 2020-12-18 CN claimed
US-20200375967-A1 COMPOSITIONS OF PSILOCYBIN AND ANALOGS TURTLE BEAR HOLDINGS, LLC 2020-12-03 US claimed
CN-106581738-A Superabsorbent medical composite haemostasis sponge and preparation method thereof 苏州纳贝通环境科技有限公司 2017-04-26 CN claimed
US-20250129022-A1 TRYPTAMINE DERIVATIVES CAAMTECH, INC. 2025-04-24 US disclosed
US-20250129022-A1 TRYPTAMINE DERIVATIVES CAAMTECH, INC. 2025-04-24 US disclosed
EP-4507692-A2 TRYPTAMINE DERIVATIVES Caamtech, Inc. (US) 2025-02-19 EP disclosed
EP-4507692-A2 TRYPTAMINE DERIVATIVES Caamtech, Inc. (US) 2025-02-19 EP disclosed
WO-2024107445-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES FREEDOM BIOSCIENCES, INC. (US) 2024-05-23 WO disclosed
US-8088805-B2 Inhibitors of histone deacetylase METHYLGENE INC. (CA) 2012-01-03 US disclosed
US-8088805-B2 Inhibitors of histone deacetylase METHYLGENE INC. (CA) 2012-01-03 US disclosed
US-20070213330-A1 Anticancer agents; antiproliferative agents METHYLGENE INC. (CA) 2007-09-13 US disclosed
US-20070213330-A1 Anticancer agents; antiproliferative agents METHYLGENE INC. (CA) 2007-09-13 US disclosed
US-7253204-B2 Antiproliferative agents METHYLGENE INC. (CA) 2007-08-07 US disclosed
US-7253204-B2 Antiproliferative agents METHYLGENE INC. (CA) 2007-08-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070213330-A1 Anticancer agents; antiproliferative agents HDAC1, HDAC11, HDAC5 HTR2A 4267/4885KDM4E 258/4885ALDH1A1 680/4885
US-20200375967-A1 COMPOSITIONS OF PSILOCYBIN AND ANALOGS PNMT, NES, GAP43 HTR2A 97/4885KDM4E 3272/4885ALDH1A1 3982/4885
US-20250129022-A1 TRYPTAMINE DERIVATIVES INMT, SLC6A4, HTR5A HTR2A 8/4885KDM4E 2149/4885ALDH1A1 4419/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.