Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4428614 | 0.80 | NPSR1 (0.44) | NPSR1MAPTHSD17B10ATMTDP1 | |
| SCHEMBL28581000 | 0.79 | NPSR1 (0.48) | NPSR1TRPM8KDM4EHPGDATM | |
| SCHEMBL9348371 | 0.79 | NPSR1 (0.48) | NPSR1TRPM8KDM4EHPGDATM | |
| SCHEMBL744078 | 0.79 | NPSR1 (0.40) | NPSR1TRPM8MAPTKDM4EHPGD | |
| SCHEMBL11361015 | 0.79 | NPSR1 (0.40) | NPSR1TRPM8MAPTKDM4EHPGD | |
| SCHEMBL742918 | 0.79 | NPSR1 (0.40) | NPSR1TRPM8MAPTKDM4EHPGD | |
| SCHEMBL4467640 | 0.76 | NPSR1 (0.44) | NPSR1KDM4EHPGDHSD17B10ATM | |
| SCHEMBL6851360 | 0.76 | LMNA (0.56) | NPSR1MAPTHSD17B10TDP1ALDH1A1 | |
| SCHEMBL28777147 | 0.72 | NPSR1 (0.41) | NPSR1ATMTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL14693878 | 0.72 | ATM (0.42) | NPSR1ATMTDP1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1028521-C | Therapeutic agents | BOOTS CO PLC (GB) | 1995-05-24 | — | — | CN | disclosed |
| CN-1072173-A | Therapeutical agent | BOOTS CO PLC (GB) | 1993-05-19 | — | — | CN | disclosed |