SCHEMBL742918

SCHEMBL742918

O=C(/C=C\C(=O)ON(Cl)c1ccccc1)ON(Cl)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.40
TRPM8 Q7Z2W7 3/20 0.39
MAPT P10636 2/20 0.39
KDM4E B2RXH2 1/20 0.39
HPGD P15428 1/20 0.39
HSD17B10 Q99714 1/20 0.39
ALDH1A1 P00352 3/20 0.38
KMT2A Q03164 2/20 0.38
RAB9A P51151 2/20 0.38
NPC1 O15118 1/20 0.38
POLB P06746 1/20 0.38
HTT P42858 1/20 0.38
HCAR2 Q8TDS4 3/20 0.38
ATM Q13315 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MEN1 O00255 1/20 0.35
HDAC3 O15379 1/20 0.34
HDAC4 P56524 1/20 0.34
HDAC1 Q13547 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27324937 0.79 NPSR1 (0.43) NPSR1TRPM8MAPTKDM4EHPGD
SCHEMBL744078 0.76 NPSR1 (0.40) NPSR1TRPM8MAPTKDM4EHPGD
SCHEMBL11361015 0.76 NPSR1 (0.40) NPSR1TRPM8MAPTKDM4EHPGD
SCHEMBL28160782 0.73 ALDH1A1 (0.44) NPSR1ALDH1A1KMT2ARAB9ANPC1
SCHEMBL27373581 0.72 PAM (0.53) HPGDALDH1A1KMT2ARAB9ANPC1
SCHEMBL28571248 0.71 TP53 (0.49) NPSR1MAPTHPGDALDH1A1KMT2A
Fumaric Acid SCHEMBL5478624 0.68 HCAR2 (0.46) NPSR1TRPM8MAPTKDM4EALDH1A1
Maleic Acid SCHEMBL5478620 0.68 HCAR2 (0.46) NPSR1TRPM8MAPTKDM4EALDH1A1
SCHEMBL28188601 0.68 ALDH1A1 (0.34) NPSR1TRPM8HPGDALDH1A1KMT2A
SCHEMBL28194436 0.68 ALDH1A1 (0.39) NPSR1MAPTKDM4EHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 304 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2431028-B1 FAST-DISSOLVING ORAL FILM FOR EFFECTIVELY CONCEALING UNPLEASANT TASTES CHABIO & DIOSTECH CO LTD (KR) 2017-07-12 EP claimed
US-9492379-B2 Quickly soluble oral film dosage containing steviosides as a unpleasant taste masking agent CHABIO & DIOSTECH CO., LTD. (KR) 2016-11-15 US claimed
US-20130039932-A1 QUICKLY SOLUBLE ORAL FILM DOSAGE CONTAINING STEVIOSIDES AS A UNPLEASANT TASTE MASKING AGENT CHABIO & DIOSTECH CO., LTD. (KR) 2013-02-14 US claimed
WO-2012134770-A1 HONEY COMPOSITION AVERY DENNISON CORPORATION (US) 2012-10-04 WO claimed
US-20120156229-A1 QUICKLY SOLUBLE ORAL FILM DOSAGE CONTAINING STEVIOSIDES AS A UNPLEASANT TASTE MASKING AGENT CHABIO & DIOSTECH CO. LTD (KR) 2012-06-21 US claimed
EP-2431028-A2 FAST-DISSOLVING ORAL FILM FOR EFFECTIVELY CONCEALING UNPLEASANT TASTES Chabio & Diostech Co., Ltd. (KR) 2012-03-21 EP claimed
CN-1090477-C Ibuprofen-containing solid composition SS PHARMACEUTICAL CO (JP) 2002-09-11 CN claimed
US-6265412-B1 MIXTURE WITH ANTIHISTAMINE TAISHO PHARMACEUTICAL CO., LTD. (JP) 2001-07-24 US claimed
EP-1080730-A1 MINOXIDIL COMPOSITIONS FOR EXTERNAL USE TAISHO PHARMACEUTICAL CO., LTD (JP) 2001-03-07 EP claimed
CN-1109745-A Ibuprofen-containing solid composition SS PHARMACEUTICAL CO (JP) 1995-10-11 CN claimed
EP-0254978-A1 Substained-release drug preparation Eisai Co., Ltd. (JP) 1988-02-03 EP claimed
JP-5310599-A None JP disclosed
JP-11302167-A None JP disclosed
US-20260144747-A1 SYRUP PREPARATION CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2026-05-28 US disclosed
US-20250262097-A1 MEDICAL DRESSINGS AND USES THEREOF MARINE BIOLOGY & ENVIRONMENTAL TECHNOLOGIES, LLC (US) 2025-08-21 US disclosed
EP-0081438-A2 Adhesive bandage NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) 1983-06-15 EP disclosed
EP-0063604-A1 MUCOUS MEMBRANE-ADHERING FILM PREPARATION AND PROCESS FOR ITS PREPARATION NIPPON SODA CO., LTD. (JP) 1982-11-03 EP disclosed
US-4218433-A Constant-rate eluting tablet and method of producing same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1980-08-19 US disclosed
US-4130555-A FOODS, COSMETICS NIPPI INCORPORATED (JP) 1978-12-19 US disclosed
US-4059686-A SODIUM POLYACRYLATE NIPPON KAYAKU KABUSHIKI KAISHA (JA) 1977-11-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260144747-A1 SYRUP PREPARATION ALK, IRAK1, IRAK3 NPSR1 2432/4885TRPM8 3354/4885MAPT 928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.