SCHEMBL27329178

SCHEMBL27329178

CCOC(=O)C1CN(Cc2ccccc2)CC12CNC2

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.47
SIGMAR1 Q99720 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
ATM Q13315 1/20 0.46
USP30 Q70CQ3 1/20 0.43
CCR8 P51685 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
KDM4E B2RXH2 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4509900 0.89 ALDH1A1 (0.50) ALDH1A1SIGMAR1L3MBTL1ATMUSP30
SCHEMBL27372315 0.88 ALDH1A1 (0.42) ALDH1A1MEN1KMT2ACYP3A4CYP2D6
SCHEMBL30751751 0.87 L3MBTL1 (0.49) ALDH1A1SIGMAR1L3MBTL1ATMUSP30
SCHEMBL22864682 0.87 L3MBTL1 (0.49) ALDH1A1SIGMAR1L3MBTL1ATMUSP30
SCHEMBL16053764 0.86 L3MBTL1 (0.48) ALDH1A1SIGMAR1L3MBTL1ATMUSP30
SCHEMBL27262462 0.85 S1PR5 (0.48) ALDH1A1SIGMAR1L3MBTL1MEN1KMT2A
SCHEMBL30751712 0.84 SIGMAR1 (0.48) ALDH1A1SIGMAR1L3MBTL1ATMUSP30
Hydrochloric Acid SCHEMBL30720687 0.84 S1PR5 (0.47) ALDH1A1SIGMAR1L3MBTL1MEN1KMT2A
Hydrochloric Acid SCHEMBL30720802 0.84 S1PR5 (0.47) ALDH1A1SIGMAR1L3MBTL1MEN1KMT2A
SCHEMBL4105884 0.83 L3MBTL1 (0.49) ALDH1A1SIGMAR1L3MBTL1ATMUSP30

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260034123-A1 CDK2 INHIBITORS AND METHODS OF USING THE SAME CEDILLA THERAPEUTICS INC (US) 2026-02-05 US disclosed
EP-4562016-A2 CDK2 INHIBITORS AND METHODS OF USING THE SAME Cedilla Therapeutics, Inc. (US) 2025-06-04 EP disclosed
EP-4562015-A2 CDK2 INHIBITORS AND METHODS OF USING THE SAME Cedilla Therapeutics, Inc. (US) 2025-06-04 EP disclosed
US-12065445-B2 CDK2 inhibitors and methods of using the same CEDILLA THERAPEUTICS, INC. (US) 2024-08-20 US disclosed
US-20240174680-A1 CDK2 INHIBITORS AND METHODS OF USING THE SAME CEDILLA THERAPEUTICS, INC. (US) 2024-05-30 US disclosed
WO-2024026483-A2 CDK2 INHIBITORS AND METHODS OF USING THE SAME CEDILLA THERAPEUTICS, INC. (US) 2024-02-01 WO disclosed
WO-2024026483-A2 CDK2 INHIBITORS AND METHODS OF USING THE SAME CEDILLA THERAPEUTICS, INC. (US) 2024-02-01 WO disclosed
WO-2024026481-A2 CDK2 INHIBITORS AND METHODS OF USING THE SAME CEDILLA THERAPEUTICS, INC. (US) 2024-02-01 WO disclosed
WO-2024026481-A2 CDK2 INHIBITORS AND METHODS OF USING THE SAME CEDILLA THERAPEUTICS, INC. (US) 2024-02-01 WO disclosed
EP-4284365-A1 CDK2 INHIBITORS AND METHODS OF USING THE SAME Cedilla Therapeutics, Inc. (US) 2023-12-06 EP disclosed
CN-117177744-A CDK2 inhibitors and methods of use thereof 塞迪拉治疗股份有限公司 2023-12-05 CN disclosed
US-20230109076-A1 CDK2 INHIBITORS AND METHODS OF USING THE SAME CEDILLA THERAPEUTICS, INC. 2023-04-06 US disclosed
WO-2022165513-A1 CDK2 INHIBITORS AND METHODS OF USING THE SAME CEDILLA THERAPEUTICS, INC. (US) 2022-08-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260034123-A1 CDK2 INHIBITORS AND METHODS OF USING THE SAME CDK2, CDK1, CDK20 ALDH1A1 4103/4885SIGMAR1 1926/4885L3MBTL1 1574/4885
US-20240174680-A1 CDK2 INHIBITORS AND METHODS OF USING THE SAME CDK2, CDK20, CDK2AP2 ALDH1A1 4363/4885SIGMAR1 4814/4885L3MBTL1 1570/4885
US-20230109076-A1 CDK2 INHIBITORS AND METHODS OF USING THE SAME CDK2, CDK20, CDK2AP2 ALDH1A1 4363/4885SIGMAR1 4814/4885L3MBTL1 1570/4885
US-12065445-B2 CDK2 inhibitors and methods of using the same CDK2, CDK20, CDK1 ALDH1A1 3879/4885SIGMAR1 4786/4885L3MBTL1 2548/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.