SCHEMBL273322

SCHEMBL273322

C[Si](O)(c1ccccc1)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 3/20 0.59
NR1H3 Q13133 3/20 0.59
ESR1 P03372 1/20 0.50
ESR2 Q92731 1/20 0.50
MAPT P10636 1/20 0.39
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
NR1I2 O75469 3/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
GLA P06280 1/20 0.35
CA3 P07451 1/20 0.35
CA4 P22748 1/20 0.35
CA9 Q16790 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CA14 Q9ULX7 1/20 0.35
LMNA P02545 1/20 0.35
TSHR P16473 1/20 0.35
ALOX12 P18054 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10383089 0.97 NR1H2 (0.57) NR1H2NR1H3ESR1ESR2MAPT
SCHEMBL28255925 0.97 NR1H2 (0.57) NR1H2NR1H3ESR1ESR2MAPT
SCHEMBL1931860 0.82 HPGD (0.63) NR1H2NR1H3ESR1ESR2CES2
SCHEMBL271787 0.81 ESR1 (0.50) NR1H2NR1H3ESR1ESR2MAPT
SCHEMBL28912 0.81 ESR1 (0.50) NR1H2NR1H3ESR1ESR2MAPT
SCHEMBL439492 0.80 ESR1 (0.48) NR1H2NR1H3ESR1ESR2MAPT
SCHEMBL31081430 0.79 NR1I2 (0.52) NR1H2NR1H3ESR1ESR2MAPT
Potassium SCHEMBL31414604 0.79 ESR1 (0.48) NR1H2NR1H3ESR1ESR2MAPT
SCHEMBL4276199 0.79 ESR1 (0.48) NR1H2NR1H3ESR1ESR2MAPT
SCHEMBL2143983 0.79 ESR1 (0.48) NR1H2NR1H3ESR1ESR2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 712 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121574717-A Rock self-water absorption inhibitor and preparation method and application thereof 中国石油大学(华东) 2026-02-27 CN claimed
CN-120037974-A Preparation method and application of nickel homogeneous hydrogenation catalyst 中国石油天然气股份有限公司 2025-05-27 CN claimed
CN-119730479-A TOPCon battery and preparation method and assembly thereof 唐山海泰新能科技股份有限公司 2025-03-28 CN claimed
CN-117684183-A Metal organic catalyst, preparation method and application thereof 贵研铂业股份有限公司 2024-03-12 CN claimed
CN-115403810-B High oleophobic pipette tip and preparation method thereof 浙江首康生物科技有限公司 2023-06-27 CN claimed
CN-115403810-A High-oleophobic pipette head and preparation method thereof 浙江首康生物科技有限公司 2022-11-29 CN claimed
CN-114410168-A Water-based paint capable of forming large-particle salient points and preparation method thereof 安徽捷翁新材料科技有限公司 2022-04-29 CN claimed
CN-108291031-B Polymetaloxane, method for producing same, composition thereof, cured film, method for producing same, member provided with same, and electronic component 东丽株式会社 2021-06-15 CN claimed
CN-104327268-B Siloxane copolymer containing ethyl phenyl silica chain links and preparation method thereof 杭州师范大学 2017-05-10 CN claimed
CN-104327268-A Siloxane copolymer containing ethyl phenyl silica chain links and preparation method thereof UNIV HANGZHOU NORMAL 2015-02-04 CN claimed
US-5097055-A PRODUCTION OF METHYLPHENYLTRISILOXANE SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-03-17 US claimed
US-5057550-A With a photoinitiator for cationic cure, electronics coating DOW CORNING CORPORATION (US) 1991-10-15 US claimed
EP-0450957-A2 Production of methylphenyltrisiloxane SHIN-ETSU CHEMICAL CO., LTD. (JP) 1991-10-09 EP claimed
EP-0431809-A2 Epoxy-silanol functional UV curable polymers DOW CORNING CORPORATION (US) 1991-06-12 EP claimed
EP-0278157-A2 A rubber composition Shin-Etsu Chemical Co., Ltd. (JP) 1988-08-17 EP claimed
US-4714733-A VULCANIZABLE BLEND OF RUBBER, UNSATURATED POLYSILOXANE, SILICA FILLER, AND THIOCARBAMYL-CONTAINING ORGANOSILANE SHIN-ETSU CHEMICAL CO., LTD. (JP) 1987-12-22 US claimed
US-4677139-A SILICONES FEINMANN BERNHARD P P (CH) 1987-06-30 US claimed
US-4324873-A Organosilicon-organometal compositions as epoxy curing catalysts TOKYO SHIBAURA DENKI KABUSHIKI KAISAHA (JP) 1982-04-13 US claimed
US-4039666-A ANTICONVULSANT PHENYLSILANES DOW CORNING CORPORATION (US) 1977-08-02 US claimed
US-4035332-A Water-soluble silicone-modified resin compositions SHIN-ETSU CHEMICAL CO., (JA) 1977-07-12 US claimed