SCHEMBL271787

SCHEMBL271787

C[Si](O)(O)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.50
ESR2 Q92731 1/20 0.50
NR1H2 P55055 2/20 0.43
NR1H3 Q13133 2/20 0.43
MAPT P10636 1/20 0.39
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
NR1I2 O75469 3/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
GLA P06280 1/20 0.35
CA3 P07451 1/20 0.35
CA4 P22748 1/20 0.35
CA9 Q16790 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CA14 Q9ULX7 1/20 0.35
LMNA P02545 1/20 0.35
TSHR P16473 1/20 0.35
ALOX12 P18054 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL272363 0.83 ESR1 (0.38) ESR1ESR2NR1H2NR1H3NR1I2
SCHEMBL273322 0.81 NR1H2 (0.59) ESR1ESR2NR1H2NR1H3MAPT
SCHEMBL28912 0.81 ESR1 (0.50) ESR1ESR2NR1H2NR1H3MAPT
SCHEMBL439492 0.80 ESR1 (0.48) ESR1ESR2NR1H2NR1H3MAPT
Potassium SCHEMBL31414604 0.79 ESR1 (0.48) ESR1ESR2NR1H2NR1H3MAPT
SCHEMBL4276199 0.79 ESR1 (0.48) ESR1ESR2NR1H2NR1H3MAPT
SCHEMBL2143983 0.79 ESR1 (0.48) ESR1ESR2NR1H2NR1H3MAPT
SCHEMBL31081430 0.79 NR1I2 (0.52) ESR1ESR2NR1H2NR1H3MAPT
SCHEMBL29217062 0.79 ESR1 (0.48) ESR1ESR2NR1H2NR1H3MAPT
SCHEMBL10383089 0.79 NR1H2 (0.57) ESR1ESR2NR1H2NR1H3MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 566 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026098028-A1 BORON-CONTAINING ORGANIC SILICON, OPTICAL ADHESIVE, ORGANIC SILICON OCA, AND PREPARATION METHOD THEREFOR AND USE THEREOF 广东派乐玛新材料科技有限公司 2026-05-15 WO claimed
CN-118956221-B Weather-resistant industrial paint and preparation method thereof 佛山涂邦德新材料科技有限公司 2024-12-24 CN claimed
US-11592945-B2 Dielectric siloxane particle films and devices having the same INKRON OY (FI) 2023-02-28 US claimed
CN-113105622-B Modified polyphenyl ether, thermosetting polyphenyl ether composition and application thereof 中山大学 2022-05-13 CN claimed
US-11289666-B2 Electrically conductive siloxane particle films, and devices with the same INKRON OY (FI) 2022-03-29 US claimed
CN-113801327-A Preparation method of methyl phenyl silanediol 仙桃市格瑞化学工业有限公司 2021-12-17 CN claimed
CN-113105622-A Modified polyphenyl ether, thermosetting polyphenyl ether composition and application thereof 中山大学 2021-07-13 CN claimed
US-20170152350-A1 Method of making a siloxane polymer composition INKRON OY (FI) 2017-06-01 US claimed
EP-3158004-A1 A METHOD OF MAKING A SILOXANE POLYMER COMPOSITION Inkron Oy (FI) 2017-04-26 EP claimed
WO-2015193558-A1 A METHOD OF MAKING A SILOXANE POLYMER COMPOSITION INKRON OY (FI) 2015-12-23 WO claimed
US-5391691-A Melt condensing am aromatic diol compound and a carbonic acid diester in the presence of an interesterification catalyst and co-presence of an organosilicon compound MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1995-02-21 US claimed
EP-0431809-B1 Epoxy-silanol functional UV curable polymers DOW CORNING (US) 1995-01-04 EP claimed
EP-0288209-B1 Polyimide resin compositions MITSUI PETROCHEMICAL IND (JP) 1994-07-06 EP claimed
EP-0594175-A1 Process for producing aromatic polycarbonate MITSUBISHI CHEMICAL CORPORATION (JP) 1994-04-27 EP claimed
US-5091014-A Polycarboxylic acid and organosilicon compound NISSEI PLAN, INC. (JP) 1992-02-25 US claimed
US-4885329-A CONTAINING A SILICONE COMPONENT AND INORGANIC FILLER; SEMICONDUCTORS, PACKAGING MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-12-05 US claimed
EP-0288209-A1 Polyimide resin compositions MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-10-26 EP claimed
US-4544728-A Storage-stable thermosetting compositions comprising imido prepolymers RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1985-10-01 US claimed
US-4238591-A BIS-MALEIMIDE, SILANEDIOL OR SILOXANE RHONE-POULENC INDUSTRIES (FR) 1980-12-09 US claimed
US-4039666-A ANTICONVULSANT PHENYLSILANES DOW CORNING CORPORATION (US) 1977-08-02 US claimed