Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25088470 | 0.81 | LMNA (0.41) | NR1H2ALDH1A1LMNAMAPTESR2 | |
| SCHEMBL27333768 | 0.79 | GRIA3 (0.40) | ENPP2GRIA3GRIA4SCD5MAPK1 | |
| SCHEMBL30903376 | 0.79 | ENPP2 (0.42) | NR1H2ALDH1A1LMNAMAPTESR2 | |
| SCHEMBL24969714 | 0.79 | ENPP2 (0.42) | NR1H2ALDH1A1LMNAMAPTESR2 | |
| SCHEMBL30903370 | 0.79 | ENPP2 (0.42) | NR1H2ALDH1A1LMNAMAPTESR2 | |
| SCHEMBL12795832 | 0.78 | GPR119 (0.54) | NR1H2ALDH1A1LMNAMAPTESR2 | |
| SCHEMBL1583382 | 0.78 | ESR2 (0.52) | NR1H2ALDH1A1LMNAMAPTESR2 | |
| SCHEMBL76458 | 0.78 | NR1H2 (0.54) | NR1H2ALDH1A1LMNAMAPTESR2 | |
| SCHEMBL22650348 | 0.78 | NR1H2 (0.46) | NR1H2ALDH1A1LMNAMAPTESR2 | |
| SCHEMBL22650415 | 0.78 | MAPT (0.46) | NR1H2ALDH1A1LMNAMAPTESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097355-A1 | DEUBIQUITINASE-TARGETING CHIMERAS AND RELATED METHODS | VICINITAS THERAPEUTICS, INC. (US) | 2024-05-10 | — | — | WO | disclosed |