Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tyrosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 15/20 | 0.46 |
| ▸ | NPY1R | P25929 | 8/20 | 0.46 |
| ▸ | NPY2R | P49146 | 6/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tyrosine SCHEMBL28889524 | 0.95 | NPY4R (0.48) | NPY4RNPY1RNPY2RNPY5R | |
| Tyrosine SCHEMBL27431939 | 0.95 | NPY4R (0.42) | NPY4RNPY1RNPY2RNPY5RTUBB4A | |
| Tyrosine SCHEMBL27677075 | 0.94 | NPY4R (0.43) | NPY4RNPY1RNPY2RNPY5RTUBB4A | |
| Dl-Tryptophan SCHEMBL27458897 | 0.92 | TUBB4A (0.48) | NPY2RTUBB4ATUBBTUBA3CTUBA1B | |
| Tyrosine SCHEMBL27692833 | 0.92 | SLC7A5 (0.42) | NPY4RNPY1RNPY2R | |
| Dl-Tryptophan SCHEMBL27780062 | 0.91 | TUBB4A (0.48) | NPY2RTUBB4ATUBBTUBA3CTUBA1B | |
| Arginine SCHEMBL27456489 | 0.91 | NPY4R (0.39) | NPY4RNPY1RNPY2RNPY5RTUBB4A | |
| Arginine SCHEMBL27398911 | 0.91 | MMP2 (0.43) | NPY4RNPY1RNPY2RNPY5RTUBB4A | |
| Tyrosine SCHEMBL27448866 | 0.91 | NPY4R (0.39) | NPY4RNPY1RNPY2RNPY5RTUBB4A | |
| Arginine SCHEMBL28861114 | 0.90 | NPY4R (0.40) | NPY4RNPY1RNPY2RNPY5RTUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1043297-C | Meat quality improving additive | ANIMAL HUSBANDRY & VETERINARY (CN) | 1999-05-12 | — | — | CN | disclosed |
| CN-1120895-A | Meat quality improving additive | MOUDING COUNTY ANIMAL HUSBANDR (CN) | 1996-04-24 | — | — | CN | disclosed |