Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dl-Tryptophan. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 2/20 | 0.48 |
| ▸ | TUBB | P07437 | 2/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.48 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.48 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.48 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.48 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.48 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.48 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.47 |
| ▸ | KISS1R | Q969F8 | 4/20 | 0.45 |
| ▸ | GHSR | Q92847 | 6/20 | 0.45 |
| ▸ | NPY2R | P49146 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dl-Tryptophan SCHEMBL27780062 | 0.99 | TUBB4A (0.48) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Dl-Tryptophan SCHEMBL27971563 | 0.95 | TUBB4A (0.49) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Tyrosine SCHEMBL27334545 | 0.92 | NPY4R (0.46) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Dl-Tryptophan SCHEMBL27361088 | 0.92 | KDM4E (0.48) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Tryptophan SCHEMBL27389650 | 0.91 | TUBB4A (0.44) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Dl-Tryptophan SCHEMBL4777903 | 0.90 | KDM4E (0.49) | KISS1R | |
| Tryptophan SCHEMBL4777905 | 0.90 | KDM4E (0.49) | KISS1R | |
| Dl-Tryptophan SCHEMBL28764380 | 0.90 | KDM4E (0.42) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Dl-Tryptophan SCHEMBL29078368 | 0.90 | NPBWR1 (0.50) | NPBWR1KISS1R | |
| Tryptophan SCHEMBL27661296 | 0.89 | TUBB4A (0.48) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1144056-A | Dayueliang pumpkin powder and its preparation method | WANG GUIHE (CN) | 1997-03-05 | — | — | CN | disclosed |