Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | F2R | P25116 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29261731 | 0.88 | GAA (0.38) | DDR1KDM4EGAAMAPK1ALDH1A1 | |
| SCHEMBL10745488 | 0.79 | EGFR (0.39) | KDM4EGAAMAPK1KMT2AMEN1 | |
| SCHEMBL20556837 | 0.73 | MIF (0.48) | SMN1; SMN2KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL1626113 | 0.73 | MIF (0.48) | SMN1; SMN2KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL29960917 | 0.73 | ABCB11 (0.49) | DDR1KDM4EGAAMAPK1ALDH1A1 | |
| SCHEMBL24730488 | 0.72 | PGR (0.41) | DDR1KDM4EGAAMAPK1ALDH1A1 | |
| SCHEMBL15143953 | 0.72 | MAPK1 (0.38) | DDR1KDM4EGAAMAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8663111 | 0.71 | MIF (0.47) | SMN1; SMN2KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL29960430 | 0.71 | DDR1 (0.36) | DDR1KDM4EGAAMAPK1ALDH1A1 | |
| SCHEMBL1626970 | 0.71 | SCN5A (0.46) | CYP1A2CYP2C19RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1046711-C | Unsaturated hydroxyalkyl quinoline carboxylic acids as leukotriene antagonists | MERCK FROSST CANADA INC (CA) | 1999-11-24 | — | — | CN | disclosed |
| CN-1061407-A | Unsaturated hydroxyalkyl quinoline carboxylic acids as leukotriene antagonists | MERCK FROSST CANADA INC (CA) | 1992-05-27 | — | — | CN | disclosed |