Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | YTHDF3 | Q7Z739 | 1/20 | 0.32 |
| ▸ | YTHDF1 | Q9BYJ9 | 1/20 | 0.32 |
| ▸ | YTHDF2 | Q9Y5A9 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7965645 | 0.77 | KDM4C (0.40) | GPR84 | |
| SCHEMBL10095166 | 0.75 | GPR84 (0.53) | GPR84CA1ALDH1A1LMNA | |
| SCHEMBL1362732 | 0.67 | GPR84 (0.53) | GPR84CA1ALDH1A1LMNAYTHDF3 | |
| SCHEMBL11662039 | 0.67 | GPR84 (0.46) | GPR84CA1ALDH1A1LMNAYTHDF3 | |
| SCHEMBL11497510 | 0.66 | CYP3A4 (0.46) | ALDH1A1LMNA | |
| SCHEMBL28818278 | 0.66 | GPR84 (0.51) | GPR84CA1ALDH1A1LMNAYTHDF3 | |
| SCHEMBL3393557 | 0.64 | LOXL2 (0.41) | CA1ALDH1A1LMNA | |
| SCHEMBL2181657 | 0.64 | GPR84 (0.50) | GPR84CA1ALDH1A1LMNAYTHDF3 | |
| SCHEMBL3418337 | 0.63 | GPR84 (0.59) | GPR84 | |
| SCHEMBL3475870 | 0.62 | GPR84 (0.44) | GPR84CA1ALDH1A1LMNAYTHDF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1043473-C | 8-substituted xanthines as selective adenosine receptor agents | MERRELL DOW PHARMA (US) | 1999-05-26 | — | — | CN | disclosed |
| CN-1122599-A | 8-substituted xanthines as selective adenosine receptor agents | MERRELL DOW PHARMA (US) | 1996-05-15 | — | — | CN | disclosed |