Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27523629 | 0.89 | THRB (0.42) | SMN1; SMN2THRBATML3MBTL1EPHX1 | |
| SCHEMBL1101398 | 0.82 | EPHX1 (0.39) | SMN1; SMN2THRBATML3MBTL1EPHX1 | |
| SCHEMBL27335896 | 0.82 | LTA4H (0.36) | SMN1; SMN2THRBATML3MBTL1EPHX1 | |
| SCHEMBL1101396 | 0.82 | EPHX1 (0.39) | SMN1; SMN2THRBATML3MBTL1EPHX1 | |
| SCHEMBL6889610 | 0.80 | CHRM1 (0.46) | — | |
| SCHEMBL6889603 | 0.80 | CHRM1 (0.46) | — | |
| SCHEMBL7546509 | 0.77 | EPHX2 (0.46) | SMN1; SMN2EPHX1ALDH1A1KDM4EACE | |
| SCHEMBL16099214 | 0.76 | SMN1; SMN2 (0.51) | SMN1; SMN2THRBATML3MBTL1EPHX1 | |
| SCHEMBL6897337 | 0.71 | LTA4H (0.38) | — | |
| SCHEMBL6897332 | 0.71 | LTA4H (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1046525-C | Compounds containing a fused bicyclic ring and processes therefor | BRISTOL MYERS SQUIBB CO (US) | 1999-11-17 | — | — | CN | disclosed |