Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9164330 | 0.86 | MAPT (0.41) | POLBALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL9278136 | 0.82 | MAPT (0.51) | POLBALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL9846124 | 0.82 | RPS6KB1 (0.40) | POLBALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL9170296 | 0.81 | KDM4E (0.44) | POLBALDH1A1KDM4EMAPTGAA | |
| SCHEMBL9846107 | 0.81 | PDE3B (0.41) | ALDH1A1KDM4EMAPTTDP1LMNA | |
| SCHEMBL9283645 | 0.80 | MAPT (0.48) | POLBALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL9846175 | 0.80 | PDE3B (0.38) | POLBALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL9168694 | 0.80 | PDE3B (0.42) | ALDH1A1KDM4EMAPTTDP1LMNA | |
| SCHEMBL27337640 | 0.80 | PDE3B (0.45) | ALDH1A1KDM4EMAPTSMN1; SMN2KMT2A | |
| SCHEMBL9432629 | 0.79 | MEN1 (0.47) | KDM4EMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1062138-A | The synergy of HIV reverse transcriptase inhibitors | MERCK & CO INC (US) | 1992-06-24 | — | — | CN | disclosed |