Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | MATK | P42679 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.40 |
| ▸ | NEK4 | P51957 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.40 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.40 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.40 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9432629 | 0.83 | MEN1 (0.47) | MAPTCYP1A2MEN1KMT2AKDM4E | |
| SCHEMBL27337641 | 0.82 | POLB (0.49) | LMNAMAPTL3MBTL1POLBMEN1 | |
| SCHEMBL9846085 | 0.81 | POLB (0.34) | RPS6KB1MAPTPOLBKMT2AGAA | |
| SCHEMBL9168694 | 0.76 | PDE3B (0.42) | LMNAMAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL9164330 | 0.76 | MAPT (0.41) | LMNAMAPTL3MBTL1POLBMEN1 | |
| SCHEMBL27925718 | 0.75 | ABCB1 (0.43) | RPS6KB1ROCK2CHEK2PRKACAAKT1 | |
| SCHEMBL9846107 | 0.75 | PDE3B (0.41) | LMNAMAPTL3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL6367001 | 0.73 | KMT2A (0.35) | LMNAMAPTNPC1RAB9ACYP1A2 | |
| SCHEMBL9170296 | 0.72 | KDM4E (0.44) | MAPTCYP1A2CYP3A4POLBGAA | |
| SCHEMBL9846165 | 0.72 | PDE3B (0.41) | LMNAMAPTL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462800-A2 | Inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | disclosed |