SCHEMBL2733765

SCHEMBL2733765

c1ccc(-c2cc(-c3cccnn3)c(-c3ccccc3)c3c2-c2cccc4cccc-3c24)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 5/20 0.41
HTR2A P28223 2/20 0.36
DHODH Q02127 1/20 0.34
ALDH1A1 P00352 2/20 0.33
TSHR P16473 2/20 0.33
MAPK1 P28482 2/20 0.33
HSD17B10 Q99714 2/20 0.33
TP53 P04637 1/20 0.33
HPGD P15428 1/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
HIF1A Q16665 1/20 0.33
HTR2B P41595 1/20 0.33
TNF P01375 1/20 0.33
GRM5 P41594 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
SLC6A2 P23975 1/20 0.32
SLC6A3 Q01959 1/20 0.32
SIRT2 Q8IXJ6 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28667607 0.84 GABRG2 (0.38) HTR2CHTR2ADHODHGRM5TOP1
SCHEMBL2733743 0.84 GRM5 (0.41) ALDH1A1TSHRMAPK1HSD17B10TP53
SCHEMBL2158220 0.83 ALDH1A1 (0.47) ALDH1A1TSHRMAPK1HSD17B10TP53
SCHEMBL2734566 0.80 TNF (0.45) ALDH1A1TSHRMAPK1HSD17B10TP53
SCHEMBL16658479 0.80 GRM5 (0.43) ALDH1A1MAPK1TP53HPGDGRM5
SCHEMBL16658502 0.80 GRM5 (0.41) DHODHALDH1A1TSHRMAPK1HSD17B10
SCHEMBL76389 0.80 ALDH1A1 (0.44) ALDH1A1TSHRMAPK1HSD17B10TP53
SCHEMBL16859291 0.80 ALDH1A1 (0.44) ALDH1A1TSHRMAPK1HSD17B10TP53
SCHEMBL251545 0.80 CYP11B1 (0.48) ALDH1A1TSHRMAPK1HSD17B10HPGD
SCHEMBL16658498 0.79 GRM5 (0.40) ALDH1A1MAPK1TP53HPGDGRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8088500-B2 OLED device with fluoranthene electron injection materials GLOBAL OLED TECHNOLOGY LLC (US) 2012-01-03 US disclosed
US-8088500-B2 OLED device with fluoranthene electron injection materials GLOBAL OLED TECHNOLOGY LLC (US) 2012-01-03 US disclosed
US-20100117520-A1 OLED DEVICE WITH FLUORANTHENE ELECTRON INJECTION MATERIALS GLOBAL OLED TECHNOLOGY LLC 2010-05-13 US disclosed
US-20100117520-A1 OLED DEVICE WITH FLUORANTHENE ELECTRON INJECTION MATERIALS GLOBAL OLED TECHNOLOGY LLC 2010-05-13 US disclosed