SCHEMBL2733766

SCHEMBL2733766

c1ccc(-c2cc(-c3ccnnc3)c(-c3ccccc3)c3c2-c2cccc4cccc-3c24)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNF P01375 1/20 0.38
SIRT2 Q8IXJ6 1/20 0.36
BRAF P15056 1/20 0.35
ALDH1A1 P00352 4/20 0.35
TSHR P16473 3/20 0.35
MAPK1 P28482 2/20 0.35
HSD17B10 Q99714 2/20 0.35
HPGD P15428 2/20 0.35
TP53 P04637 1/20 0.35
CASP1 P29466 1/20 0.35
CASP7 P55210 1/20 0.35
HIF1A Q16665 1/20 0.35
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
CDK4 P11802 1/20 0.33
CCND1 P24385 1/20 0.33
RAB9A P51151 1/20 0.33
WNT3A P56704 2/20 0.32
KAT6A Q92794 1/20 0.32
PDE10A Q9Y233 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2734566 0.85 TNF (0.45) TNFALDH1A1TSHRMAPK1HSD17B10
SCHEMBL2158220 0.85 ALDH1A1 (0.47) TNFALDH1A1TSHRMAPK1HSD17B10
SCHEMBL251545 0.84 CYP11B1 (0.48) TNFALDH1A1TSHRMAPK1HSD17B10
SCHEMBL2734079 0.83 CYP11B1 (0.49) TNFALDH1A1TSHRMAPK1HSD17B10
SCHEMBL16658503 0.83 NOTUM (0.44) TNFALDH1A1TSHRMAPK1HSD17B10
SCHEMBL16859291 0.82 ALDH1A1 (0.44) TNFALDH1A1TSHRMAPK1HSD17B10
SCHEMBL76389 0.82 ALDH1A1 (0.44) TNFALDH1A1TSHRMAPK1HSD17B10
SCHEMBL2734065 0.81 ATM (0.43) TNFALDH1A1TSHRMAPK1HSD17B10
SCHEMBL16658476 0.81 NOTUM (0.42) TNFALDH1A1TSHRMAPK1HSD17B10
SCHEMBL16658474 0.81 IMPDH2 (0.42) TNFALDH1A1TSHRMAPK1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8088500-B2 OLED device with fluoranthene electron injection materials GLOBAL OLED TECHNOLOGY LLC (US) 2012-01-03 US disclosed
US-8088500-B2 OLED device with fluoranthene electron injection materials GLOBAL OLED TECHNOLOGY LLC (US) 2012-01-03 US disclosed
WO-2010114838-A1 OLED DEVICE CONTAINING A SILYL-FLUORANTHENE DERIVATIVE GLOBAL OLED TECHNOLOGY LLC (US) 2010-10-07 WO disclosed
US-20100244677-A1 OLED DEVICE CONTAINING A SILYL-FLUORANTHENE DERIVATIVE GLOBAL OLED TECHNOLOGY LLC 2010-09-30 US disclosed
US-20100244677-A1 OLED DEVICE CONTAINING A SILYL-FLUORANTHENE DERIVATIVE GLOBAL OLED TECHNOLOGY LLC 2010-09-30 US disclosed
US-20100117520-A1 OLED DEVICE WITH FLUORANTHENE ELECTRON INJECTION MATERIALS GLOBAL OLED TECHNOLOGY LLC 2010-05-13 US disclosed
US-20100117520-A1 OLED DEVICE WITH FLUORANTHENE ELECTRON INJECTION MATERIALS GLOBAL OLED TECHNOLOGY LLC 2010-05-13 US disclosed