Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.31 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | RHOC | P08134 | 1/20 | 0.30 |
| ▸ | RHOA | P61586 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10443547 | 0.86 | THRB (0.34) | HTR2ASLC6A4KCNH2TLR8TLR7 | |
| SCHEMBL9332364 | 0.85 | HTR2A (0.36) | HTR2ASLC6A4KCNH2TLR8CYP1A2 | |
| SCHEMBL9331754 | 0.80 | NR4A1 (0.44) | TLR8CYP1A2CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL8938797 | 0.77 | CYP1A2 (0.41) | CYP1A2CYP3A4CYP2C19ALDH1A1SMN1; SMN2 | |
| SCHEMBL9334657 | 0.77 | CYP3A4 (0.37) | HTR2ASLC6A4KCNH2TLR8CYP1A2 | |
| SCHEMBL8938831 | 0.76 | MEN1 (0.38) | TLR8SMN1; SMN2TLR7L3MBTL1RHOC | |
| SCHEMBL9332068 | 0.75 | TLR8 (0.44) | TLR8CYP1A2CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL9582221 | 0.74 | MAOB (0.41) | TLR8CYP3A4ALDH1A1SMN1; SMN2TLR7 | |
| SCHEMBL9332004 | 0.72 | TDP1 (0.45) | CYP1A2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL4493478 | 0.72 | NPBWR1 (0.46) | HTR2ASLC6A4KCNH2TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1040367-A | Heterogeneous ring compound | ICI PLC (GB) | 1990-03-14 | — | — | CN | disclosed |