Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | CDK9 | P50750 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | FPR2 | P25090 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5758743 | 0.93 | TSHR (0.54) | TSHRTP53EPHX1EPHX2CDK9 | |
| SCHEMBL14935624 | 0.80 | SMN1; SMN2 (0.48) | TSHRTP53EPHX1EPHX2CDK9 | |
| SCHEMBL3396184 | 0.77 | TSHR (0.58) | TSHRTP53EPHX1EPHX2CDK9 | |
| SCHEMBL9042394 | 0.76 | CCKBR (0.41) | TSHRTP53EPHX1EPHX2CDK9 | |
| SCHEMBL31299898 | 0.76 | KDM4E (0.39) | ALDH1A1MAPTCA12CA1CA9 | |
| SCHEMBL26809469 | 0.74 | HTT (0.54) | SMN1; SMN2ALDH1A1HTTKMT2AMEN1 | |
| Diphenylurea SCHEMBL133103 | 0.73 | SMN1; SMN2 (1.00) | TSHRTP53EPHX1EPHX2CDK9 | |
| SCHEMBL8961559 | 0.73 | TP53 (0.57) | TSHRTP53EPHX1EPHX2CDK9 | |
| SCHEMBL4394297 | 0.72 | CYP1A2 (0.57) | ALDH1A1HTTGAAMAPT | |
| Diphenylurea SCHEMBL28431956 | 0.71 | SMN1; SMN2 (0.94) | TSHRTP53EPHX1EPHX2CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1049846-A | Glutarimide with weeding activity | ROHM & HAAS (US) | 1991-03-13 | — | — | CN | disclosed |