SCHEMBL27339232

SCHEMBL27339232

CC(C)=CC1OC(=O)c2ccccc21

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.44
MAPT P10636 2/20 0.40
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
LMNA P02545 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
HPGD P15428 1/20 0.40
CYP2C19 P33261 1/20 0.40
HSD17B10 Q99714 2/20 0.38
KDM4E B2RXH2 2/20 0.38
POLB P06746 1/20 0.37
GLA P06280 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
GAA P10253 1/20 0.36
HIF1A Q16665 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11199598 0.77 ALDH1A1 (0.50) ALDH1A1MAPTKMT2AMEN1LMNA
SCHEMBL27340485 0.76 ALDH1A1 (0.46) ALDH1A1MAPTKMT2AMEN1LMNA
SCHEMBL631497 0.76 ALDH1A1 (0.48) ALDH1A1MAPTKMT2AMEN1LMNA
SCHEMBL9132333 0.75 ALDH1A1 (0.44) ALDH1A1MAPTLMNAHSD17B10KDM4E
SCHEMBL29992849 0.75 RAB9A (0.40) ALDH1A1MAPTKMT2AMEN1LMNA
SCHEMBL10772876 0.75 RAB9A (0.40) ALDH1A1MAPTKMT2AMEN1LMNA
SCHEMBL31315628 0.72 ALDH1A1 (0.53) ALDH1A1MAPTKMT2AMEN1LMNA
SCHEMBL15314185 0.72 ALDH1A1 (0.53) ALDH1A1MAPTKMT2AMEN1LMNA
SCHEMBL228037 0.72 ALDH1A1 (0.53) ALDH1A1MAPTKMT2AMEN1LMNA
SCHEMBL18705376 0.72 ALDH1A1 (0.53) ALDH1A1MAPTKMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1041725-C Method for synthetising 3-butenyl phthalide UNIV LANZHOU (CN) 1999-01-20 CN disclosed
CN-1086814-A A kind of method of synthetic 3-butylidene phthalide UNIV LANZHOU (CN) 1994-05-18 CN disclosed