Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.45 |
| ▸ | PGR | P06401 | 6/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.45 |
| ▸ | AR | P10275 | 3/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21497120 | 0.75 | PGR (0.43) | PGRNR3C1NR3C2ARKIF11 | |
| SCHEMBL4190362 | 0.74 | PTGS2 (0.72) | PTGS2KIF11 | |
| SCHEMBL27363292 | 0.73 | CA2 (0.50) | PTGS2 | |
| SCHEMBL10300269 | 0.73 | PTGS2 (0.62) | PTGS2KIF11PTGS1 | |
| SCHEMBL7677302 | 0.73 | PTGS2 (0.62) | PTGS2KIF11PTGS1 | |
| SCHEMBL27340103 | 0.72 | ALAD (0.61) | PTGS2KIF11 | |
| SCHEMBL27353969 | 0.72 | PTGS2 (0.50) | PTGS2KIF11PTGS1 | |
| SCHEMBL27447182 | 0.72 | PTGS2 (0.45) | PTGS2PTGS1 | |
| SCHEMBL27340099 | 0.71 | AURKA (0.49) | PTGS2LRRK2KIF11 | |
| Hydrochloric Acid SCHEMBL27363291 | 0.71 | LOX (0.48) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1059142-A | New thiophene derivant | FUJISAWA PHARMACEUTICAL CO (JP) | 1992-03-04 | — | — | CN | disclosed |