Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.47 |
| ▸ | TLR2 | O60603 | 1/20 | 0.47 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.47 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29432755 | 1.00 | ERN1 (0.56) | ERN1ALDH1A1TSHRKDM4ETDP1 | |
| SCHEMBL6098384 | 0.85 | ALDH1A1 (0.63) | ERN1ALDH1A1TSHRKDM4ETDP1 | |
| SCHEMBL365682 | 0.84 | ALDH1A1 (0.63) | ERN1ALDH1A1TSHRKDM4ETDP1 | |
| SCHEMBL25688773 | 0.84 | CYP1A2 (0.53) | ERN1ALDH1A1TSHRKDM4ETDP1 | |
| SCHEMBL275895 | 0.83 | ALDH1A1 (0.66) | ERN1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL9049946 | 0.83 | NFE2L2 (0.55) | ERN1ALDH1A1TSHRKDM4ETDP1 | |
| SCHEMBL18177606 | 0.82 | ERN1 (0.62) | ERN1ALDH1A1TSHRKDM4ETDP1 | |
| SCHEMBL8686048 | 0.80 | ALDH1A1 (0.55) | ERN1ALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL29750759 | 0.80 | ALDH1A1 (0.55) | ERN1ALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL21816457 | 0.80 | ALDH1A1 (0.55) | ERN1ALDH1A1KDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 444 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111592535-B | Preparation method of EGFR mutation resistant inhibitor EAI045 | 通化师范学院 | 2021-07-20 | — | — | CN | claimed |
| CN-111592535-A | Preparation method of EGFR mutation resistant inhibitor EAI045 | 通化师范学院 | 2020-08-28 | — | — | CN | claimed |
| US-12630511-B2 | Benzamide derivative, preparation method therefor, and pharmaceutical composition comprising same as active ingredient for prevention or treatment of cancer | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2026-05-19 | — | — | US | disclosed |
| EP-4707264-A2 | COMPOUNDS AND THE USE THEREOF IN METATHESIS REACTIONS | Verbio SE (DE) | 2026-03-11 | — | — | EP | disclosed |
| EP-4122924-B1 | COMPOUNDS AND THE USE THEREOF IN METATHESIS REACTIONS | VERBIO SE (DE) | 2025-11-19 | — | — | EP | disclosed |
| US-12454532-B2 | Inhibiting cyclic AMP-responsive element-binding protein (CREB) binding protein (CBP) | FORMA THERAPEUTICS, INC. (US) | 2025-10-28 | — | — | US | disclosed |
| US-20250326744-A1 | PIPERAZINE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION | FUJIFILM CORPORATION (JP) | 2025-10-23 | — | — | US | disclosed |
| US-20250304583-A1 | INHIBITING G CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN (CREB) BINDING PROTEIN (CBP) | FORMA THERAPEUTICS, INC. | 2025-10-02 | — | — | US | disclosed |
| US-12378242-B2 | Inhibiting CREB binding protein (CBP) | FORMA THERAPEUTICS, INC. (US) | 2025-08-05 | — | — | US | disclosed |
| WO-2025124496-A1 | COMPOUND CONTAINING PYRAZOLE RING AND BICYCLIC HETEROARYL GROUP, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 正大天晴药业集团股份有限公司 | 2025-06-19 | — | — | WO | disclosed |
| CN-119816484-A | Novel piperazine derivative or salt thereof and pharmaceutical composition | 富士胶片株式会社 | 2025-04-11 | — | — | CN | disclosed |
| US-4772625-A | 1,3-dioxan-5-yl-hexenoic acids | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-09-20 | — | — | US | disclosed |
| EP-0266980-A2 | Pharmaceutical compositions, comprising a 2,4-diphenyl-1,3-dioxane derivative and an inhibitor of thromboxane A2 synthesis | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-05-11 | — | — | EP | disclosed |
| EP-0225175-A2 | Dihydropyridine derivatives, processes for their preparation and pharmaceutical compositions thereof | FISONS plc (GB) | 1987-06-10 | — | — | EP | disclosed |
| EP-0202086-A2 | Hexenoic acids | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-11-20 | — | — | EP | disclosed |
| EP-0201354-A2 | 2,4-Diphenyl-1,3-Dioxanes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-11-12 | — | — | EP | disclosed |
| US-4448971-A | Hypoglycemic 5-phenyl-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1984-05-15 | — | — | US | disclosed |
| US-4407811-A | Hypoglycemic 5-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1983-10-04 | — | — | US | disclosed |
| US-4399296-A | TRIMETHYLSILYL CYANOHYDRIN INTERMEDIATES | PFIZER INC. (US) | 1983-08-16 | — | — | US | disclosed |
| US-4367234-A | HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1983-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250304583-A1 | INHIBITING G CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN (CREB) BINDING PROTEIN (CBP) | CREBBP, CREB1, EP300 | ERN1 650/4885ALDH1A1 3783/4885TSHR 2531/4885 |
| US-12378242-B2 | Inhibiting CREB binding protein (CBP) | CREBBP, EP300, CREB1 | ERN1 637/4885ALDH1A1 3592/4885TSHR 2892/4885 |
| US-12630511-B2 | Benzamide derivative, preparation method therefor, and pharmaceutical composition comprising same as active ingredient for prevention or treatment of cancer | EGFR, ERBB2, KRAS | ERN1 4044/4885ALDH1A1 1072/4885TSHR 1637/4885 |
| US-12454532-B2 | Inhibiting cyclic AMP-responsive element-binding protein (CREB) binding protein (CBP) | CREBBP, CREB1, EP300 | ERN1 593/4885ALDH1A1 3548/4885TSHR 2457/4885 |
| US-20250326744-A1 | PIPERAZINE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION | ABCB11, ABCC1, SLC11A2 | ERN1 3094/4885ALDH1A1 774/4885TSHR 3952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.