Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 19/20 | 0.59 |
| ▸ | EPAS1 | Q99814 | 19/20 | 0.59 |
| ▸ | EP300 | Q09472 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7819460 | 0.77 | MAPT (0.56) | HIF1AEPAS1 | |
| SCHEMBL7820055 | 0.76 | HIF1A (0.60) | HIF1AEPAS1EP300 | |
| SCHEMBL2009830 | 0.75 | HIF1A (0.52) | HIF1AEPAS1 | |
| SCHEMBL2562218 | 0.74 | HIF1A (1.00) | HIF1AEPAS1EP300 | |
| SCHEMBL9196234 | 0.72 | HIF1A (0.50) | HIF1AEPAS1EP300 | |
| SCHEMBL9475096 | 0.72 | HIF1A (0.52) | HIF1AEPAS1EP300 | |
| SCHEMBL8003071 | 0.71 | HIF1A (0.49) | HIF1AEPAS1EP300 | |
| SCHEMBL7835766 | 0.71 | HIF1A (0.49) | HIF1AEPAS1EP300 | |
| SCHEMBL12338169 | 0.71 | COXFA4 (0.59) | HIF1AEPAS1EP300 | |
| SCHEMBL5870597 | 0.70 | ALDH1A1 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1061970-A | 1-benzopyran derivatives, its method for making and treatment effectiveness thereof with step-down and vasodilator activity | SANKYO CO (JP) | 1992-06-17 | — | — | CN | disclosed |