SCHEMBL27341802

SCHEMBL27341802

CCCCc1sccc1S(N)(=O)=O

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA2 P00918 16/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CA1 P00915 8/20 0.38
CA9 Q16790 7/20 0.38
CA7 P43166 4/20 0.38
CA5A P35218 2/20 0.38
CA5B Q9Y2D0 2/20 0.38
CA12 O43570 4/20 0.38
TSHR P16473 1/20 0.38
LMNA P02545 2/20 0.35
RECQL P46063 1/20 0.35
HPGD P15428 1/20 0.34
CA4 P22748 2/20 0.33
CA3 P07451 1/20 0.33
CA6 P23280 1/20 0.33
CA13 Q8N1Q1 1/20 0.33
CA14 Q9ULX7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6157351 0.95 CA2 (0.47) CA2SMN1; SMN2CA1CA9CA7
SCHEMBL9663866 0.74 CA1 (0.33) CA2CA1CA9CA7CA5A
SCHEMBL4362446 0.74 CA2 (0.39) CA2CA1CA9CA7CA5A
SCHEMBL1164460 0.74 CA2 (0.47) CA2SMN1; SMN2CA1CA9CA7
SCHEMBL28105935 0.72 TYR (0.41) CA2CA1TSHRLMNAHPGD
SCHEMBL20228012 0.72 LTB4R (0.41) TSHRLMNARECQLHPGD
SCHEMBL13477743 0.72 SKP2 (0.40) CA2SMN1; SMN2
SCHEMBL10837835 0.70 CA1 (0.38) CA2CA1CA9CA7CA5A
SCHEMBL4457865 0.70 LTB4R (0.45)
SCHEMBL8815622 0.70 ALOX5 (0.44) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1046280-C Novel thiophenesulfonylurea derivative and herbicidal composition containing the same KOREA RES INST CHEM TECH (KR) 1999-11-10 CN disclosed
CN-1220264-A Novel thiophenesulfonylurea derivatives KOREA RES INST CHEM TECH (KR) 1999-06-23 CN disclosed
CN-1134701-A Novel thiophenesulfonylurea derivatives and herbicidal compositions containing the same KOREA RES INST CHEM TECH (KR) 1996-10-30 CN disclosed
CN-86103880-A Contain herbicide of thiophene sulfonamide compounds and preparation method thereof 1987-01-21 CN disclosed