Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.52 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1790721 | 0.93 | TUBB1 (0.50) | ERN1TUBB1KDM4ERAB9AHPGD | |
| SCHEMBL31166254 | 0.92 | TUBB1 (0.61) | ERN1TUBB1KDM4ERAB9AHPGD | |
| SCHEMBL5449064 | 0.88 | MDM2 (0.52) | ERN1KDM4ERAB9AHPGDALDH1A1 | |
| SCHEMBL18199319 | 0.87 | ERN1 (0.50) | ERN1HPGDALDH1A1SMN1; SMN2MDM2 | |
| SCHEMBL15728130 | 0.85 | TUBB1 (0.61) | ERN1TUBB1KDM4ERAB9AALDH1A1 | |
| SCHEMBL4067770 | 0.85 | MDM2 (0.50) | ERN1KDM4ERAB9AHPGDALDH1A1 | |
| SCHEMBL271557 | 0.84 | LMNA (0.51) | ERN1TUBB1KDM4ERAB9AALDH1A1 | |
| SCHEMBL5885093 | 0.83 | TUBB1 (0.59) | ERN1TUBB1KDM4ERAB9AALDH1A1 | |
| SCHEMBL29142665 | 0.83 | ALDH1A1 (0.48) | TUBB1KDM4ERAB9AHPGDALDH1A1 | |
| SCHEMBL30712871 | 0.83 | ALDH1A1 (0.48) | TUBB1KDM4ERAB9AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8133898-B2 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-13 | — | — | US | disclosed |
| CN-102212274-A | Triphenylamine-phenyl organic dye and application thereof | UNIV TIANJIN TECHNOLOGY | 2011-10-12 | — | — | CN | disclosed |
| US-20100137310-A1 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-03 | — | — | US | disclosed |
| WO-2008121506-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137310-A1 | RENIN INHIBITORS | REN, ACE, PRSS3 | ERN1 2576/4885TUBB1 4074/4885KDM4E 3124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.