Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.31 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18502936 | 0.83 | ALOX15 (0.46) | LTA4HHTR2ASMN1; SMN2HTR2CKCNH2 | |
| Hydrochloric Acid SCHEMBL18668753 | 0.82 | ALOX15 (0.44) | LTA4HHTR2ASMN1; SMN2HTR2CKCNH2 | |
| SCHEMBL22922810 | 0.80 | KEAP1 (0.42) | LTA4HHTR2ASMN1; SMN2HTR2CKCNH2 | |
| SCHEMBL12935790 | 0.80 | SMN1; SMN2 (0.45) | LTA4HHTR2ASMN1; SMN2 | |
| SCHEMBL14734035 | 0.77 | DRD2 (0.45) | SMN1; SMN2 | |
| SCHEMBL357355 | 0.76 | CYP2D6 (0.34) | LTA4HSMN1; SMN2KDR | |
| SCHEMBL27777191 | 0.76 | CYP2D6 (0.34) | LTA4HSMN1; SMN2KDR | |
| SCHEMBL4317822 | 0.76 | CYP2D6 (0.34) | LTA4HSMN1; SMN2KDR | |
| SCHEMBL12465593 | 0.75 | LTA4H (0.37) | LTA4HHTR2AHTR2CKCNH2 | |
| SCHEMBL12465710 | 0.75 | SLC18A3 (0.41) | LTA4HHTR2ASMN1; SMN2HTR2CKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1058262-C | Novel 1-phenylalkanone 5-HT4Receptor ligands | SYNTEX INC (US) | 2000-11-08 | — | — | CN | disclosed |
| CN-1124485-A | Novel 1-phenylalkanone 5-HT4Receptor ligands | SYNTEX A INC (US) | 1996-06-12 | — | — | CN | disclosed |