Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.31 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 3/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1992521 | 0.67 | ALDH1A1 (0.55) | KMT2AALDH1A1GAAHTTMAPT | |
| SCHEMBL7334697 | 0.67 | GRK2 (0.44) | KMT2AALDH1A1GAAROCK2ROCK1 | |
| SCHEMBL7143432 | 0.62 | FSCN1 (0.36) | ALDH1A1MAPTSMN1; SMN2LMNAPOLB | |
| SCHEMBL744075 | 0.62 | RAB9A (0.65) | KMT2AHTTMAPTNPSR1SMN1; SMN2 | |
| SCHEMBL31118681 | 0.61 | SMN1; SMN2 (0.43) | ALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL30417525 | 0.60 | KMT2A (0.49) | KMT2AALDH1A1HTTMAPTNPSR1 | |
| SCHEMBL3927134 | 0.60 | CYP17A1 (0.50) | KMT2AALDH1A1GAAHTTNTRK1 | |
| SCHEMBL24269714 | 0.60 | HTR6 (0.50) | ALDH1A1GAAMAPT | |
| SCHEMBL10338665 | 0.60 | CHRM5 (0.48) | KMT2AALDH1A1GAAROCK2ROCK1 | |
| SCHEMBL9015374 | 0.59 | TSHR (0.46) | KMT2AALDH1A1GAAHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1046710-C | New 4-aminopyridines, process for preparing the same and medicaments containing the same | LUOHE DIAGNOSTIC EQUIPMENT CO (DE) | 1999-11-24 | — | — | CN | disclosed |
| CN-1119858-A | Aminopyridines, process for their preparation and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM GMBH (DE) | 1996-04-03 | — | — | CN | disclosed |