SCHEMBL303370

SCHEMBL303370

c1ccc2c(c1)Nc1ccc3ccccc3c1O2

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 7/20 0.55
DHODH Q02127 1/20 0.40
TAAR1 Q96RJ0 1/20 0.38
TDP1 Q9NUW8 2/20 0.38
HSD17B10 Q99714 2/20 0.38
ALDH1A1 P00352 1/20 0.38
CYP2A6 P11509 1/20 0.38
TSHR P16473 1/20 0.38
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
GAA P10253 2/20 0.36
NPC1 O15118 1/20 0.36
MAPT P10636 1/20 0.36
RAB9A P51151 1/20 0.36
NOX1 Q9Y5S8 1/20 0.36
HPRT1 P00492 1/20 0.35
HTR2B P41595 1/20 0.35
MCL1 Q07820 1/20 0.34
NPSR1 Q6W5P4 1/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29531401 1.00 ALOX5 (0.55) ALOX5DHODHTAAR1TDP1HSD17B10
SCHEMBL22133297 0.92 ALOX5 (0.50) ALOX5DHODHTAAR1TDP1HSD17B10
SCHEMBL22362222 0.87 ALDH1A1 (0.46) ALOX5TAAR1TDP1HSD17B10ALDH1A1
SCHEMBL22131486 0.82 TDP1 (0.50) ALOX5TAAR1TDP1HSD17B10ALDH1A1
SCHEMBL22961244 0.81 AHR (0.39) ALOX5TAAR1TDP1HSD17B10ALDH1A1
SCHEMBL22131480 0.81 TDP1 (0.49) ALOX5TAAR1TDP1HSD17B10ALDH1A1
SCHEMBL18162295 0.81 TAAR1 (0.41) TAAR1TDP1HSD17B10ALDH1A1CYP2A6
SCHEMBL22087145 0.80 KMT2A (0.41) ALOX5TAAR1TDP1MEN1KMT2A
SCHEMBL22131439 0.78 TDP1 (0.34) ALOX5TAAR1TDP1HSD17B10ALDH1A1
Phenoxazine SCHEMBL18770789 0.76 ALOX5 (0.85) ALOX5DHODHTDP1ALDH1A1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11898074-B2 Blue thermally activated delayed fluorescence material, synthesis method thereof, and use thereof WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2024-02-13 US claimed
US-20210253947-A1 BLUE THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL, SYNTHESIS METHOD THEREOF, AND USE THEREOF WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2021-08-19 US claimed
WO-2020237901-A1 THERMALLY ACTIVATED DELAYED FLUORESCENCE BLUE LIGHT MATERIAL, SYNTHESIS METHOD THEREFOR AND USE THEREOF 武汉华星光电半导体显示技术有限公司 2020-12-03 WO claimed
EP-3397718-A1 FLUORESCENT PARTICULATE MATERIAL L'Oréal (FR) 2018-11-07 EP claimed
WO-2017114877-A1 FLUORESCENT PARTICULATE MATERIAL L'OREAL (FR) 2017-07-06 WO claimed
EP-1781675-B1 PHOSPHONATE FLUORESCENT DYES AND CONJUGATES EPOCH BIOSCIENCES INC (US) 2014-03-26 EP claimed
JP-2012500860-A 2012-01-12 JP claimed
US-7671218-B2 Phosphonate fluorescent dyes and conjugates Elitech Holdings B.V. (NL) 2010-03-02 US claimed
US-20100047859-A1 SILICA-BASED FLUORESCENT NANOPARTICLES SNU R&DB FOUNDATION (KR) 2010-02-25 US claimed
WO-2010021512-A2 SILICA-BASED FLUORESCENT NANOPARTICLES SNU R&DB FOUNDATION (KR) 2010-02-25 WO claimed
WO-2006020947-A2 PHOSPHONATE FLUORESCENT DYES AND CONJUGATES EPOCH BIOSCIENCES, INC. (US) 2006-02-23 WO claimed
WO-2006008239-A2 LUMINESCENT SILICON OXIDE FLAKES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-01-26 WO claimed
US-20050176066-A1 Compounds and methods for fluorescent labeling EPOCH BIOSCIENCES, INC. (US) 2005-08-11 US claimed
US-20050171340-A1 COMPOUNDS AND METHODS FOR FLUORESCENT LABELING EPOCH BIOSCIENCES, INC. (US) 2005-08-04 US claimed
US-20050159606-A1 Compounds and methods for fluorescent labeling EPOCH BIOSCIENCES, INC. (US) 2005-07-21 US claimed
WO-2005040357-A2 COMPOUNDS AND METHODS FOR FLUORESCENT LABELING EPOCH BIOSCIENCES, INC. (US) 2005-05-06 WO claimed
EP-1466176-A2 COMPOUNDS AND METHODS FOR FLUORESCENT LABELING Epoch Biosciences, Inc. (US) 2004-10-13 EP claimed
US-20030152518-A1 Detection by increased uptake of fluorophore glucose or deoxyglucose conjugates in cancerous and pre-cancerous cells relative to normal cells. THRESHOLD PHARMACEUTICALS, INC. 2003-08-14 US claimed
WO-2003059149-A2 METHODS FOR CANCER IMAGING THRESHOLD PHARMACEUTICALS, INC. (US) 2003-07-24 WO claimed
WO-2003023357-A2 COMPOUNDS AND METHODS FOR FLUORESCENT LABELING EPOCH BIOSCIENCES, INC. (US) 2003-03-20 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030152518-A1 Detection by increased uptake of fluorophore glucose or deoxyglucose conjugates in cancerous and pre-cancerous cells relative to normal cells. SLC2A1, SLC2A4, SLC2A8 ALOX5 4375/4885DHODH 492/4885TAAR1 3915/4885
US-20050176066-A1 Compounds and methods for fluorescent labeling HLCS, GLB1, TUBB ALOX5 1685/4885DHODH 101/4885TAAR1 3280/4885
US-20050171340-A1 COMPOUNDS AND METHODS FOR FLUORESCENT LABELING HLCS, GLB1, TUBB ALOX5 1685/4885DHODH 101/4885TAAR1 3280/4885
US-20100047859-A1 SILICA-BASED FLUORESCENT NANOPARTICLES NOXO1, NOX3, SOS1 ALOX5 2800/4885DHODH 678/4885TAAR1 3099/4885
US-20050159606-A1 Compounds and methods for fluorescent labeling TFEB, HLCS, PFAS ALOX5 2235/4885DHODH 333/4885TAAR1 3655/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.