Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | EDNRA | P25101 | 1/20 | 0.42 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27344759 | 0.84 | PIM3 (0.35) | LMNAKMT2AMEN1ABCC4PKM | |
| SCHEMBL27335103 | 0.82 | TOP2A (0.48) | KMT2AMEN1RPS6KB1MATKDYRK1A | |
| SCHEMBL27323899 | 0.82 | LMNA (0.37) | LMNAKMT2AMEN1KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL27336325 | 0.82 | TOP2A (0.47) | KMT2AMEN1RPS6KB1MATKDYRK1A | |
| SCHEMBL10440800 | 0.76 | PIM3 (0.64) | LMNAKMT2AMEN1ABCC4PKM | |
| Hydrochloric Acid SCHEMBL10440903 | 0.74 | PIM3 (0.61) | LMNAKMT2AMEN1ABCC4PKM | |
| Hydrochloric Acid SCHEMBL27422188 | 0.74 | TOP2A (0.43) | LMNAKMT2AMEN1ABCC4KDM4E | |
| SCHEMBL10278301 | 0.72 | LMNA (0.60) | LMNAKMT2AMEN1ABCC4PKM | |
| SCHEMBL10440945 | 0.70 | LMNA (0.53) | LMNAKMT2AMEN1ABCC4PKM | |
| SCHEMBL13284365 | 0.69 | LMNA (0.51) | LMNAKMT2AMEN1ABCC4PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1045972-A | 5-replaces-1,4-dihydro-4-oxo-naphthyridine-3-carboxylic acid (ester) antimicrobial drug | BRISTOL MYERS SQUIBB CO (US) | 1990-10-10 | — | — | CN | claimed |