Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM3 | Q86V86 | 2/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | MATK | P42679 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 4/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.33 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.32 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.32 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27345669 | 0.84 | LMNA (0.46) | PIM3RPS6KB1MATKDYRK1AMAPKAPK3 | |
| SCHEMBL27335103 | 0.82 | TOP2A (0.48) | PIM3RPS6KB1MATKDYRK1AMAPKAPK3 | |
| SCHEMBL27323899 | 0.82 | LMNA (0.37) | PIM3RPS6KB1MATKDYRK1AMAPKAPK3 | |
| Hydrochloric Acid SCHEMBL27336325 | 0.82 | TOP2A (0.47) | PIM3RPS6KB1MATKDYRK1AMAPKAPK3 | |
| SCHEMBL10440652 | 0.76 | PIM3 (0.64) | PIM3RPS6KB1MATKDYRK1AMAPKAPK3 | |
| Hydrochloric Acid SCHEMBL27422188 | 0.70 | TOP2A (0.43) | TOP2ATOP2BMEN1ABCC4LMNA | |
| SCHEMBL13576352 | 0.68 | PIM3 (0.54) | PIM3RPS6KB1MATKDYRK1AMAPKAPK3 | |
| SCHEMBL27323317 | 0.67 | GSK3B (0.52) | TOP2ATOP2BMEN1KMT2A | |
| SCHEMBL27338265 | 0.66 | EPHA2 (0.52) | MEN1LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL27274912 | 0.65 | EPHA2 (0.51) | MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1045972-A | 5-replaces-1,4-dihydro-4-oxo-naphthyridine-3-carboxylic acid (ester) antimicrobial drug | BRISTOL MYERS SQUIBB CO (US) | 1990-10-10 | — | — | CN | claimed |