SCHEMBL27346508

SCHEMBL27346508

Cn1nc(C(F)(F)F)cc1S(=O)(=O)N1C[C@H]2CN(C3CCOCC3)C[C@@H]2C1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CTSK P43235 1/20 0.39
▸ TGFBR1 P36897 2/20 0.34
▸ DDR1 Q08345 4/20 0.33
▸ PTGS2 P35354 2/20 0.32
▸ PIK3CA P42336 1/20 0.32
▸ NPC1 O15118 1/20 0.32
▸ RAB9A P51151 1/20 0.32
▸ HPGD P15428 1/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ TSHR P16473 1/20 0.32
▸ SMN1; SMN2 Q16637 1/20 0.32
▸ PSEN1 P49768 1/20 0.32
▸ PSEN2 P49810 1/20 0.32
▸ APH1B Q8WW43 1/20 0.32
▸ NCSTN Q92542 1/20 0.32
▸ APH1A Q96BI3 1/20 0.32
▸ PSENEN Q9NZ42 1/20 0.32
▸ CCNE1 P24864 1/20 0.31
▸ CDK2 P24941 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27346368 1.00 CTSK (0.39) CTSKTGFBR1DDR1PTGS2PIK3CA
SCHEMBL26064882 0.89 MEN1 (0.39) CTSKDDR1HPGDMEN1KMT2A
SCHEMBL25371880 0.86 CTSK (0.37) CTSKTGFBR1DDR1PTGS2NPC1
SCHEMBL27070068 0.84 HPGD (0.46) CTSKHPGDMEN1KMT2ASMN1; SMN2
SCHEMBL30719506 0.83 MEN1 (0.33) PIK3CAHPGDMEN1KMT2AALDH1A1
SCHEMBL27346137 0.83 MEN1 (0.33) PIK3CAHPGDMEN1KMT2AALDH1A1
SCHEMBL25370553 0.82 CTSK (0.37) CTSKHPGDMEN1KMT2ATSHR
SCHEMBL25370750 0.82 CTSK (0.37) CTSKTGFBR1HPGDMEN1KMT2A
SCHEMBL25370768 0.82 CTSK (0.37) CTSKTGFBR1HPGDMEN1KMT2A
SCHEMBL26065952 0.81 MEN1 (0.38) DDR1HPGDMEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4554934-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF Biogen MA Inc. (US) 2025-05-21 — — EP claimed
CN-119731160-A Emopanamide binding protein inhibitors and uses thereof 渤健马萨诸塞州股份有限公司 2025-03-28 — — CN claimed
WO-2024015503-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2024-01-18 — — WO claimed
EP-4554934-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF Biogen MA Inc. (US) 2025-05-21 — — EP disclosed
CN-119731160-A Emopanamide binding protein inhibitors and uses thereof 渤健马萨诸塞州股份有限公司 2025-03-28 — — CN disclosed
WO-2024015503-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2024-01-18 — — WO disclosed
WO-2024015503-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2024-01-18 — — WO disclosed
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